James (Jim) Radosevich, PhD

Dr. James (Jim) A Radosevich (Ph.D.) is a Professor in the School of Dental Medicine at the University of Illinois at Chicago (UIC). From 1983 to 2004 he was an Assistant/Associate Professor and a Certified Clinical Investigator (ICH) at Northwestern University Medical School.  He has consulted for numerous companies over the last thirty-six years, received numerous national grants/awards, and been involved in all aspects of drug development and clinical trials. Dr. Radosevich has been part of six start-up biotechnology/medical companies over the past thirty years and has a history of consistently beating performance milestones.  He has held the positions of President, CEO, Chief Scientific Officer, and was the founder for five of these companies. Dr. Radosevich earned a B.S. degree in Biology at Bradley University in Peoria, Illinois in 1978 and a Ph.D. in Experimental Pathology at UIC in 1983.  He completed his postdoctoral training at Northwestern University in Tumor Cell Biology, where he established his expertise in immune recognition, immune response, and various molecular and biochemical approaches in understanding the morphology, physiology, and cell biology of human cancer. He has edited seven books, and has over four hundred published scientific papers, book chapters and abstracts, as well as 12 patents.

1.   Radosevich, James A. and A. Galsky. The Concentration of Selected Cations in Normal

and Crown-gall Tumors Obtained from Potato Disc. Plant and Cell Physiol. 20 (1):

185-192, 1979.

2.   Radosevich, James A. and R.E. Wing. Starch-based Ion Exchange Materials in Paper:

Preparation and Use in Heavy Metal Removal. Starch. 32:424-429, 1980.

3.   Rosen, S.T., Combs, S., Marder, R., Minna, J., Mulshine, J., Polovina, M., and J.A.

Radosevich. Immunohistochemical Localization of the Immunodominant Differentiation

Antigen Lacto-N-Fucopentaose III in Normal Adult and Fetal Tissues Utilizing

Monoclonal Antibodies.  Colloquium: Protides of the Biological Fluids.  H. Peeters, Ed.,

Pergamon Press, Vol. 32, 561-566, 1984.

4.   Rosen, S.T., Lambiase, E.A., Ma, Y., Radosevich, J.A., and A.L. Epstein. Monoclonal

Antibodies for Tumor Diagnosis, Staging and Therapy. Postgraduate Medicine.

77:129-134, 1985.

5.   Rosen, S.T., Goldman-Leikin, R.E., Zimmer, A.M., and J.A. Radosevich. Monoclonal

Antibodies in Cancer Therapy.  Laboratory Medicine, 15:310-314, 1985.

6.   Radosevich, J.A., Ma, Y., Lee, I., Salwen, H.R., Gould, V.E., and S.T. Rosen.

Monoclonal Antibody 44-3A6 as a Probe for a Novel Antigen Found Human Lung

Carcinomas with glandular differentiation. Cancer Research, 45:5805-5812, 1985.

7.   Lee, I., Radosevich, J.A., Rosen, S.T., Ma, Y., Combs, S.G., and V.E. Gould.

Immunohistochemistry of Lung Carcinomas Using Monoclonal Antibody 44-3A6.

Cancer Research, 45:5813-5817, 1985.

8.   Banner, B.F., Gould, V.E., Radosevich, J.A., Ma, Y., Lee, I., and S.T. Rosen.

Application of Monoclonal Antibody 44-3A6 in the Cytodiagnosis and Classification of

Pulmonary Carcinomas.  Diag Cytopathol. 1:300-307, 1985.

9.   Lee, I., Radosevich, J.A., Chejfec, G., Ma, Y., Warren, W.H., Rosen, S.T. and V.E.

Gould.  Malignant Mesotheliomas:  Improved Differential Diagnosis From Lung

Adenocarcinomas Using Monoclonal Antibodies 44-3A6 and 624A12. American Journal

of Pathology. 123:497-507, 1986.

10.  Al-Gailani, F., Marder, R.J., Radosevich, J.A., Hauck, W.W., Molteni, A., and S.T.

Rosen.  Phase II Trial of Tamoxifen In Lymphocytic Leukemia. Cancer Treatment Reports.

70:1343-1344, 1986.

11.  Winter, J.N., Marder, R.J., Radosevich, J.A. and A.L. Epstein. Monoclonal Antibody

DLC-48:  An Effective Reagent For The Use In The Depletion of Malignant Lymphoma

From Human Bone Marrow.  Int.J. Cancer. 39:670-677, 1987.

12.  Rosen, S.T., Gould, V.E., Salwen, H.R., LeBeau, M.M., Lee, I., Bauer, K., Marder, R.J.,

Andersen, R., Kies, M.S., Moll, R., Franke, W.W., and J.A. Radosevich.  Characterization

of a Neuroendocrine Skin Carcinoma Cell Line:  In Vitro Comparison With Small Cell

Bronchopulmonary Neuroendocrine Carcinomas. Laboratory Investigation. 56:302-312, 1987.

13.  Lee, I., Radosevich, J.A., Ma, Y., Warren, W.H., Rosen, S.T. and V.E. Gould.

Immunohistochemical Analysis of Pulmonary Carcinomas Using Monoclonal Antibody

624-A12.  Path. Res. Pract.  182:40-47, 1987.

14.  Gould, V.E., Widenmann, B., Lee, I., Schwechheimer, K., Dockhorn-Dworniczak, B.,

Radosevich, J.A., Moll, R. and W.W. Franke. Synaptophysin Expression in

Neuroendocrine Neoplasms as Determined by Immunocytochemistry.  Am. J. Path.

126:243-257, 1987.

15.  Lee, I., Radosevich, J.A., Thor, A., Ma, Y., Schlom, J., Gould, V.E. and S.T. Rosen.

Immunohistochemical Detection of ras Oncogene Products In Pulmonary and Pleural

Neoplasms.  Virchows Arch.of Pathology.  (B) Cell Biology 53:146-153, 1987.

16.  Shambaugh, G.E., Koehler, R.R. and J.A. Radosevich.  Nutrition and Fetal Brain

Maturation.  I. Response In Vitro and In Vivo.  J. Experimental Cell Research.

172:404-416, 1987.

17.  Shambaugh, G.E., Koehler, R.R. and J.A. Radosevich.  Nutrition and Fetal Brain

Maturation.  II. The Impact of Maternal Starvation on Changing Levels of

Acetylcholinesterase and Enolase In Vitro J. Experimental Cell Research.

175:344-353,1988.

18.  Combs, S.G., Radosevich, J.A., Ma, Y., Lee, I., Gould, V.E., Battifora, H., and S.T.

Rosen.  Expression of the Antigenic Determinant Recognized by the Monoclonal

Antibody 44-3A6 on Select Human Adenocarcinomas and Normal Human Tissues.

Tumor Biology. 9:116-122, 1988.

19.  Piehl, M.R., Gould, V.E., Radosevich, J.A., Ma, Y., Warren, W.H., and S.T. Rosen.

Immunohistochemical Identification of Exocrine and Neuroendocrine Subsets of Large

Cell Lung Carcinomas. Pathology, Research and Practice. 183:675-682, 1988.

20.  Combs, S.G., Hidvegi, D.F., Ma, Y., Rosen, S.T. and J.A. Radosevich. Pleomorphic

Carcinoma of the Pancreas:  A rare case report of combined histological features of

pleomorphic adenocarcinoma and giant cell tumor of the pancreas. Diag. Cytopathol.

4:316-322, 1988.

21.  Shambaugh III, G.E., Koehler, R.R., and J.A. Radosevich. Developmental Pattern of

Poly (ADP-Ribose) Synthetase and NAD Glycohydrolase In the Brain of the Fetal and

Neonatal Rat. Neurochemical Research, 13:973-981, 1988.

22.  Kwaan, H.C., Radosevich, J.A., Xu, C.G., and D.W. Eggena. Presence of Inhibitors of

Fibrinolysis in Malignant Melanoma.  Tumor Biology. 9:301-306, 1988.

23.  Radosevich, J.A., Gould, V.E., Ma, Y., Lee, I., Thor, A., Carney, Warren, W.H.,

Schlom, J. and S.T. Rosen.  Immunohistochemical Analysis of Normal and Mutated ras

Oncogene p21 Expression in Human Pulmonary and Pleural neoplasms. Virchows Arch

of Pathology. B. 56:377-383, 1989.

24.  Radosevich, J.A., Combs, S.G., Ma, Y., Lee, I., Gould, V.E., Thor, A., Schlom, J. and

S.T. Rosen.  Expression of ras Oncogene p21 during Human Fetal Development as

determined by the Monoclonal Antibody RAP-5 and Y13-259. Virchows Arch of

Pathology. B. 56:337-344, 1989.

25.  Robinson, P.G., Eggena, D.W., Koch, A.E., and J.A. Radosevich. A Double Staining

Procedure Involving Immunohistochemical Staining with a Modified Prussian Blue

Technique for Iron. Laboratory Medicine. 20:569-571, 1989.

26.  Keep, J.C., Benson III, A.B., Sullivan, M.D., Carney, W.P., Rosen, S.T., and J.A.

Radosevich.  Immunohistochemical Analysis of Colon Adenocarcinoma with Monoclonal

Antibody 47D10 and Anti-Carcinoembryonic Antigen. Tumor Biology. 10:153-163, 1989.

27.  Zimmer, A.M., Kazikiewicz, J.M., Webber, D.I., Patel, B.A., Goldman-Leikin, R.,

Radosevich, J.A., Spies, W.G., Spies, S.M., and S.T. Rosen. Stability of Radioiodinated

Monoclonal Antibodies: In Vitro Storage and Plasma Analysis. International J. of Nuclear

Medicine and Biology. 16:691-696, 1989.

28.  Radosevich, J.A., Robinson, P.G., Rittmann-Grauer, L.S., Wilson, B., Leung, J.P.,

Maminta, M.L., Warren, W., Rosen, S.T., and V.E. Gould. Immunohistochemical

Analysis of Pulmonary Carcinomas With The Monoclonal Antibody (MCA) HYB612

Directed Against The Multidrug Resistance MDR-1 Gene Product: P-glycoprotein.

Tumor Biology. 10:252-257, 1989.

29.  Radosevich, J.A., Robinson, P.G., Carney, W.P., Warren, W., Rosen, S.T., and V.E.

Gould. Immunohistochemical Analysis of Pulmonary and Pleural Neoplasms Using a

Monoclonal Antibody (MCA) 47D10 Which Reacts With Nonspecific Cross Reacting

Antigen (NCA). Tumor Biology. 10:281-288, 1990.

30.  Pensler, J.M., Langman, C.B., Radosevich, J.A., Maninta, M.L., Mangkornkanok, M.,

Higbee, R., and A. Molteni. Sex Steroid Receptors in Normal and Dysplastic Bone

Disorders in Children. J. Bone and Mineral Research 5:493-498, 1990.

31.  Pensler, J.M., Radosevich, J.A., Higbee, R., and C.B. Langman. Osteoclast Isolated

From Membranous Bone In Children Exhibit Nuclear Estrogen and Proesterone

Receptors. J. Bone and Mineral Research 5:797-802, 1990.

32.  Jansson, D., Radosevich, J.A., Carney, W.P., Rosen, S.T., Schlom, J., Staren, E.D.,

Hyster, M.J., and V.E. Gould. Immunohistochemical Analysis of Ras Oncogene

Expression in Epithelial Neoplasms of The Colon. Cancer 6:1329-1337, 1990.

33.  Shambaugh III, G.E., Clough, D., Munari, L., Koehler, R.R., and J.A. Radosevich.

The Impact of Maternal Serum On Development of Enolase Activity In Fetal Rat Brain

Cell Culture. Expt. Cell. Res. 186:210-217, 1990.

34.  Radosevich, J.A., Noguchi, M., Rosen, S.T., and Y. Shimosato. Immunocytochemical

Analysis of Human Adenocarcinomas and Bronchioloalveolar Carcinomas of the Lung

Using The Monoclonal Antibody 44-3A6. Tumor Biology. 11:181-188, 1990.

35.  Koukoulis, G.K., Radosevich, J.A., Rosen, S.T., and V.E. Gould. Immunohistochemical

Study of Pulmonary and Pleural Tumors With Monoclonal Antibodies (MAbs) B72.3

and CSLEX-1. Virchows Arch of Pathology. B. 58:427-433, 1990.

36.  Koch, A.E., Robinson, P.G., Radosevich, J.A., and R.M. Pope. Distribution of CD45RA

and CD45RO T lymphocyte subsets in rheumatoid arthritis synovial tissue. J. Clin.

Immun. 10:192-199,1990.

37.  Koch, A.E., Haines, G.K., Rizzo, R.R., Radosevich, J.A., Pope, R.M., Robinson, P.G.,

and W.H. Pearce. Human Abdominal Aortic Aneurysms: Immunophenotypic Analysis

Suggesting an Immune Mediated Response.  Am. J. Path. 137:1199-1213, 1990.

38.  Radosevich, J.A., Siddiqui, F.S., Rosen, S.T., and W.J. Kabat. Cell Cycle and Electron

Microscopic Evaluation of the Adenocarcinoma Antigen Recognized by the Monoclonal

Antibody  44-3A6. British J. Cancer 63:86-87, 1991.

39.  Spagnolo, D.V., Witaker, D., Carrello, S., Radosevich, J.A., Rosen, S.T., and V.E.

Gould. The Use of Monoclonal Antibody 44-3A6 In Cell Blocks In the Diagnosis of

Lung Carcinoma, Carcinomas Metastatic To Lung and Pleura, and Pleural Malignant

Mesothelioma. American J. Clinical Pathology 95:322-329, 1991.

40.  Radosevich, J.A., Maminata, M.L.D., Rosen, S.T., and V.E. Gould. A Simple and

Inexpensive Approach To Determine the Amount of Paraffin Embedded Tissue

Needed For DNA Molecular Analysis Using a Rapid Extraction Procedure. Laboratory

Medicine 22:543-546, 1991.

41.  Kwaan, H.C., Keer, H.N., Radosevich, J.A., Cajot, J.-F. and R. Ernst. Components of

the Plasminogen-Plasmin System In Human Tumor Cell Lines. Sem. In Thrombosis and

Hemostasis. 17:175-182, 1991.

42.  Sinkule, J., Rosen, S.T., and J.A. Radosevich. MCA 44-3A6 Douxorubicin

(Adriamycin) Immunoconjugates: Comparative In Vitro Anti-Tumor Efficacy of

Different Conjugation Methods. Tumor Biology 12:198-206, 1991.

43.  Duda, R.B., August, C.Z., Rosen, S.T., and J.A. Radosevich. Monoclonal Antibody 44-3A6 as a Marker For Differentiation of Breast Cancer. Tumor Biology 12:254-260, 1991.

44.  Radosevich, J.A., Combs, S.G., and S.T. Rosen. Expression of the epitope recognized by the monoclonal antibody 44-3A6 During human Fetal Development. Tumor Biology 12:321-329, 1991.

45.  Deftos, L.J., Martin, E.M., Gould, V.E., A. Hoog, S.T. Rosen, and J.A. Radosevich. Parathyroid Hormone-Related Protein, Chromogranin A, and Calcitonin Gene Products In Neuroendocrine Skin Carcinoma Cell Lines. J. Bone Mineral Res. 14:113-120, 1991.

46.  Yew, W.W., Kwan, S.Y.L., Lam, K.C., Chiu, K.Y., Hsu, C., Fu, K.H., and J.A. Radosevich. Application of Monoclonal Antibody 44-3A6 In the Cytological Diagnosis of Malignant Pleural Effusion and Histological Correlation In Lung Carcinoma. Lung Cancer 7:309-316, 1991.

47.  Barch, D.H., Jacoby, R.F., Brasitus, T.A., Radosevich, J.A., Carney, W.P., and P.M. Iannaccone. Incidence of Harvey-ras Oncogene Point Mutations and Their Expression in Methylbenzylnitrosamene Induced Esophageal Tumorigenesis. Carcinogenesis 12:2373-2377, 1991.

48.  Gu, D.S., Shambaugh, G.E., Metzer, B.E., Unterman, T.G., and J.A. Radosevich. Retardation of Fetal Brain Cell Growth During Maternal starvation: Cirulating Growth Factor Versus Altered Cellular Response. Neurochemical Research 17:529-537, 1992.

49.  Mittal, B.B., Zimmer, A.M., Sathiaseelan, V., Rosen S.T., Radosevich, J.A., Rademaker, A.W., Saini, A., Pierce, M.C., Webber, I.D., and S.M., Spies. Effects of Hyperthermia and 131-I anti-CEA Monoclonal Antibody on  Human Xenografts in Nude Mice. Cancer 70:2785-2791, 1992.

50.  Ng, Y-K, Taborn, G., Ahmad, I., Radosevich, J.A., Bauer, K.D., and P. Iannaccone. Spatiotemporal Changes of ras p21 in Hepatocyte Cell Cycle During Liver Regeneration. Developmental Biology 150:352-362, 1992.

51.  Maker, V.K. and J.A. Radosevich. Reduced Tumor Cell Transfer With Contact Neodymium-Yttrium-Aluminium Garnett (Nd:YAG) Laser Scalpels.  Lasers In Surg. Med. 12:303-307, 1992.

52.  Siddiqui, F.S., Iqbal, Z., and J.A. Radosevich. Changes in the expression of the tumor-associated antigen recognized by the MCA 44-3A6 in A549 cells due to calcium. Tumor Biology, 13:142-151, 1992.

53.  Haines, G.K., Ghadge, G., Thimmappaya, B., and J.A. Radosevich. Expression of the protein kinase p68 recognized by the monoclonal antibody TJ4C4 in human lung neoplasms. Virchows Arch. Path. B., 62:151-158, 1992.

54.  Zimmer, A.M., Kuzel, T.M., Spies, W.G., Duda, R.B., Webber D.I., Kazikiewicz J.M., Radosevich, J.A., LoCicero, J., Robinson, P.G., Gilyon, K.A., Samuelson, E., Spies, S.M., Rosen, S.T., and R.T. Maguire. Comparative pharmacokinetics of In-111 and Y-90 B72.3 in patients following single dose intravenous administration. Anti-body Immunoconjugates and Radiopharmaceuticals 5:285-294, 1992.

55.  Mittal, B.B., Zimmer, A.M., Sathiaseelan, V., Saini, A., Rosen  S.T., Rademaker, A.W., Radosevich, J.A., M.C., Webber, I.D., and S.M., Spies. Hyperthermia-Induced Enhancement of 131-I anti-CEA Monoclonal Antibody on Human Colon Carcinoma Xenografts in Nude Mice.  Endocurrietharapy/Hyperthermia Oncology: An International Journal 8:217-223, 1992.

56.  Haines, G.K., Ghadge, G., Combs, S.G., Leslie, W., Thimmappaya, B., and J.A. Radosevich. Immunohistochemical Detection of  Double-Stranded RNA-Dependent Protein Kinase (P-68) With A Novel Monoclonal Antibody TJ4C4: A Case Report of An AIDS-Associated Kaposi’s Sarcoma Treated With Alpha-Interferon. Tumor Biology 13:324-329, 1993

57.  Cajulis, R.S., Szumel, R., Frias-Hidvegi, D., Combs, S.G., and J.A. Radosevich. Monoclonal antibody 44-3A6 as an adjunct in cytodiagnosis of adenocarcinomas in body fluids. Diagnostic Cytopath. 9:179-183, 1993.

58.  Radosevich, J.A., Gould, K.A., Koukoulis, G.K. Haines G.K., Rosen, S.T., Lee I, and V.E. Gould. Immunohistochemical analysis of ras oncogene p21 expression in human liver diseases. Ultrastructure. Path. 17:1-8, 1993.

59.  Radosevich, J.A., Maminta, M.L.D., and S.T. Rosen. A review of current methods to extract DNA from fixed – paraffin embedded tissues for molecular analysis. Labmedica 10:13-17, 1993.

60.  Radosevich, J.A., Haines, G.K., Elseth, K.M., Shambaugh, G.E., and V. K. Maker. A new method for the detection of viable cells in tissue sections using 3-[4,5-Dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium Bromide (MTT): An application in the assessment of tissue damage by surgical instruments. Virchow Archiv (B). 63:345-350, 1993.

61.  Haines, G.K., Ghadge, G., Becker, S., Kies, M., Pelzer, H., Thimmappaya, B., and J.A. Radosevich. Immunohistochemical Expression of The Double-Stranded RNA-Dependent Protein Kinase (P68) In Head and Neck Squamous Cell Carcinoma: Correlation with differentiation. Virchow Archiv (B) 63:289-295,1993.

62.  Shambaugh III, G.E., Radosevich, J.A., Glick R.P., Gu D.S., Metzgar, B.E., and T.G. Unterman. Insulin-like growth factors and binding proteins in the fetal rat: Alterations during maternal starvation and effects in fetal brain cell culture. Neurchem. Res. 18:695-703, 1993.

63.  Haines, G.K., Ghadge G., and J.A. Radosevich. Expression of p68 protein kinase as recognized by the monoclonal antibody TJ4C4 during human fetal development. Tumor Biol. 14:95-104, 1993.

64.  Shambaugh, G., Glick, R., Radosevich, J., and T. Unterman. Insulin-like growth factor-I and binding protein-1 (BP-1) can modulate fetal brain cell growth during maternal starvation. Ann. N. Y. Acad. Sci. 692:270-272, 1993.

65.  Haines, G.K., Becker, S., Ghadge, G., Kies, M., Pelzer, H., and J.A. Radosevich. Expression of the double-stranded RNA-dependent protein kinase (P68) in squamous cell carcinoma of the head and neck region: Prognostic implications. Archives of Otolaryngology – Head & Neck Surgery 119:1142-1147, 1993.

66.  Pensler, J.M., Ledesma, D.F., Hijjawi J., and J.A. Radosevich. Plagiocephaly: Premature unilateral closure of the coronal suture: A potentially localized disorder of cellular metabolism. Annals Plastic Surg. 32:160-165, 1994.

67.  Shambaugh III, G.E., Unterman, T.G., Goolsby, C.L., Natarajan, N., Glick, R.P., Kelly, G.C., and J.A. Radosevich. Proliferative Growth of Neonatal Cerebellar Cells in Culture: Regulation by Maternal and Male Rat Serum. Neurochem. Res. 19:297-309, 1994.

68.  Dubreuil, R., Souik, P., Haines G.K., and J.A. Radosevich. Monoclonal antibodies directed against human tumor associated antigens cross-react with Drosophila proteins in clusters. International J. of Cancer. 8:96-97, 1994.

69.  Natarajan, N., Shambaugh III, G.E., Elseth, K.M., Haines, G.K., and J.A.Radosevich. Adaptation of the Diphenylamine (DPA) Assay to a 96 Well Plate Tissue Culture Format and Comparison With the MTT Assay.  BioTechniques 17:166-171, 1994.

70.  Radosevich, J.A., Ghadge, G.D., Haines, G.K., P. Malhotra, and B. Thimmapaya. Characterization of the mouse monoclonal antibody TJ4C4 directed at human p68 kinase. Tumor Biology 15:225-262, 1994.

71.  Haines, G.K., and J.A. Radosevich. The double stranded RNA dependent protein kinase (p68) is a novel marker for differentiation in aerodigestive tumors. Proc. Inter. Cancer Congress XVI (UICC) 3:1683-1686, 1995.

72.  Radosevich, J.A., Bradley, G.S., and K.M. Elseth. Molecular cloning of the human Nag gene and the expression of the adenocarcinoma associated antigen (labyrinthin): the antigen recognized by the monoclonal antibody 44-3A6. Proc. Inter. Cancer Congress XVI (UICC) 1:237-241, 1995.

73.  Singh, C., Haines G.K., Talamonti, M.S., and J.A. Radosevich. Expression of p68 in human colon cancer correlates with cellular differentiation. Tumor Biology 16:281-289, 1995.

74.  Shambaugh, G.E., Maker, A., and J.A. Radosevich. A rapid method for simultaneous determination of protein and salt concentrations in ion exchange fractions. BioTechniques 19:725-28, 1995.

75.  Maker, V.K., Elseth, K.M., and J.A. Radosevich. Reduced In Vivo local recurrence with contact neodymium-yttrium-aluminium garnet (Nd:YAG) laser scalpels. Lasers In Surg. Med. 17:370-374, 1995.

76.  Haines, G.K., Cajulis, R.S., Hayden, R.T., Frias-Hidvegi, D., Duda, R.B., August C.Z., and J.A. Radosevich. P68 expression in breast neoplasms as detected by monoclonal antibody TJ4C4. Tumor Biology 17:5-12, 1996.

77.  Potempa, L.A., Motie M., Wright K.E., Crump B.L., Radosevich, J.A., Sakai, N., Hua, L.G., Tanaka, K., Kojima, E., and A. Tsuboi. Stimulation of megakaryocytopoiesis in mice by human Modified-C-reactive protein (mCRP). Exper. Hema. 24:258-264, 1996.

78.  Bentz, B.G., Haines, G.K., Hanson, D.G., and J.A. Radosevich. Head and neck squamous cell carcinomas express a spectrum of constitutive. Biol. Nitric Oxide Part 5, Portland Press, London, 1996.

79.  Bentz, B.G., Barnes, M.N., Haines, G.K., Lurain J.R., Hanson, D.G., and J.A. Radosevich. Cytoplamic Localization of Endothelial Constitutive Nitric Oxide Synthase in Endometrial Carcinomas. Tumor Biology. 18:290-296, 1997.

80.  Bentz, B.G., Haines III, G.K., Hanson, D.G., and J.A. Radosevich. Endothelial constitutive nitric oxide synthase (ecNOS) localization in normal and neoplastic salivary tissue. Head & Neck. 20:304-309, 1998.

81.  Pensler, J.M., Ivescu, A.S., and J.A. Radosevich. Scaphocaly: Premature closure of the Sagittal Suture: A Localized disorder of cellular Metabolism. Annals Plastic Surg. 40:48-52, 1998.

82.  Haines III, G.K., Panos, R.J., Bak, P.M., Brown, T., Zielinski, M., Leyland, J., and J.A. Radosevich.  Interfeon-Responsive Protein Kinase (p68) and Proliferating Cell Nuclear Antigen Are Inversely Distributed in Head and Neck Squamous Cell Carcinoma.  Tumor Biol. 19:52-59, 1998.

83.   Bentz, B.G., Haines, G.K., vonSchlegell, A.S., Elseth, K.M., Hanson, D.G., and J.A. Radosevich. Expression of the adenocarcinoma-related antigen recognized by monoclonal antibody 44-3A6 in salivary gland neoplasia. Otolaryng.- Head & Neck Surg. 118:603-609, 1998

84.  Zhou, Y., Gobl, A., Wang, S., Jacobsen, M.B., Janson, E.T., Haines III, G.K., J.A. Radosevich, and K. Oberg. Expression of p68 protein kinase and its prognostic significance during INF-alpha therapy in patients with carcinoid tumors. Eur. J. Cancer 34: 2046-2052, 1998.

85.  Bentz, B.G., Haines III, G.K., and J.A. Radosevich. Nitrotyrosine Implicates Nitric Oxide in Head and neck Squamous Cell Carcinoma. Proceedings of the 17th International Cancer Congress 17:547-550, 1998.

86.  Diehl, E.E., Radosevich, J.A., Haines III, G.K., Yokoo, H., and L.A. Potempa. Cellular Effects of the Modified Form of C-reactive Protein (mCRP) on Tumor Cells. Proceedings of the 17th International Cancer Congress, 17:167-170, 1998.

87.  Kresl, J.J., Potempa, L.A., Anderson, B., and J.A. Radosevich. Inhibition of Mouse Mammary Adenocarcinoma (EMT6) Growth and Metastases in Mice by a Modified Form of C-Reative Protein. Tumor Biol. 20:72-87,1999.

88.  Bentz, B.G., Haines III, G.K., Hanson, D.G., and J.A. Radosevich. Nitric oxide synthase type 3 is Increased in Squamous Hyperplasia, Dysplasia, and squamous Cell Carcinoma of the Head and Neck. Ann Otol Rhinol Laryngol. 108:781-787, 1999.

89.  Bentz, B.G., Haines, G.K., and J.A. Radosevich. Glutathione s-Transferase pi in Squamous Cell Carcinoma of the Head & Neck. Laryngoscope. 110 (20 pt 1):1642-7, 2000

90.  Bentz, B.G., Haines III, G.K., Hanson, D.G., and J.A. Radosevich. Increased protein nitrosylation in head and neck squamous cell carcinogenesis. Head & Neck 22:64-70, 2000.

91.  Diehl, E.E., Haines III, G.K., Radosevich, J.A., and L.A. Potempa. Immunohistochemical Localization of Modified C-Reactive Protein antigen in normal vascular tissue. Am J Med Sci. 319(2) 79-83, 2000.

92.  Bentz, B.G., Simmons, R.L., Haines III, G.K., and J.A. Radosevich. The Yin and Yang of Nitric Oxide. Reflections on the Physiology and Pathophysiology of NO. [Invited Review] Head & Neck. 22(1):71-83, 2000

93. Chandra, R.K., Haines III, G.K., Bentz, B.G., Shah, P., Robinson, A.M., and J.A. Radosevich. Expression of NOS3 in Reflux-Induced Lesions of the Esophagus. Otol Head Neck Surg. 124:442-7, 2001.

94. Chandra, R.K., Bentz, B.G., Haines, G.K., Robinson, A.M., and J.A. Radosevich. Expression of Glutathione s-Transferase pi in Benign Mucosa, Barrett’s Metaplasia, and Adenocarcinomaof the Esophagus. Head Neck 24:575-81, 2002.

1. Bentz, B.G., Chandra, R.K., Haines III, G.K., Robinson, A.M., Shah, P., and J.A. Radosevich. Nitric Oxide and Apoptosis in Human Head & Neck Squamous Cell Carcinoma Development. Am J Otol. Am. J Otolaryngol. 23:4-11, 2002.

96.  Altman, K.W., Haines III, G.K., Hammer, N.D., and J.A. Radosevich. The H+/K+ -ATPas (proton) Pump is Expressed in Human Laryngeal Submucoals Glands. Laryngoscope 113:1927-1930, 2003.

97.  Altman, K.W., Haines III, G.K., Vakkalanka, S.K., Keni, S.P., Kopp, P.A., and J.A. Radosevich. Identification of Thyroid Horome Receptors in the Human Larynx. . Laryngoscope 113:1931-1934, 2003.

98.   Bentz, B.G., Hammer, N.D., J.A. Radosevich, and G.K. Haines, III. Nitrosative Stress Induces DNA Strand Breaks but not Caspase Mediated Apoptosis in a Lung Cancer Cell Line. J Carcinogesis 3:1-19, 2004.

99.   Hammer, N.D., Lee, S., Vesper, B.J., Elseth, K.M., Hoffman, B.M., Barrett, A.G., and J.A. Radosevich. Charge Dependence of Cellular Uptake and Selective Antitumor Activity of Porphyrazines. J. Med. Chem. 48:8125-8133, 2005.

100.   Altman KW, Waltonen JD, Hammer ND, Haines GK III, and JA Radosevich. “Proton pump expression in human laryngeal seromucinous glands,” Otolaryngology – Head & Neck Surgery, 133: 718-724, 2005.

101.  Vesper, B. J., Lee, S., Hammer, N. D., Elseth, K. M., Barrett, A. G., Hoffman, B. M., and J.A. Radosevich.  “Developing a Structure-Function Relationship for Anionic Porphyrazines Having Selective Anti-Tumor Activity.” J. Photochem. Photobio. B: Bio. 82:180-186, 2006.

102.  Bentz, B.G., Hammer, N.D., Milash, B., Klein, S., Burnett, D.M., Radosevich, J.A., and G.K. Haines III. Nitric oxide’s kineteics and redox state determine the biological consequences in lung adenocarcinoma. Tumor Biology 28:301-11,2007.

103.  Vesper, B.J., Altman, K.W., Elseth, K.M., Haines III, G.K., Pavlova, S., Tao, L., Targan, G., and J.A. Radosevich. Gastroesophageal reflux disease (GERD): Is there more to the story? ChemMedChem, 3(4):552-559, 2008.

104.  Altman, K.W., Chhaya, V., Hammer, N.D., Pavlova, S., Vesper, B.J., Tao, L., and J.A. Radosvich. Effect of proton pump imhibitor Pantoprazole on growth and morphology of oral Lactobacillus strains. Laryngascope.118(4):599- 604, 2008.

105.  Altman, KW, Waltonen, JA, Tarjan, G, Radosevich, JA, and GK Haines. “Human Lung Mucus Glands Manifest Evidence of the H+/K+ -ATPase Proton Pump. Annual of Otology, Rhinology, and Laryngology 116:229-34, 2008.

106.  Lee, S., Vesper, B.J., Zong, H., Hammer, N.M., Elseth, K.M., Barrett, A.G.M., Hoffman, B.M., and James A. Radosevich. Synthesis and Biological Analysis of Thiotetra(ethylene glycol) monmethyl ether-  functionalized Porphyrazines: Cellular Uptake and Toxicity Studies. Metal-Based Drugs 2008:391418, 2008.

107. Wilkie, J.R., Roeske, J.C., Tiryaki, H., Smith, B.D, Radosevich, J.A. and B. Aydogan. Feasibility Study for Linac-Based Intensity Modulated Total Marrow Irradiation. Radiation Oncology, Biology & Physics 35(12):5609-18, 2008

1. Albrecht, H., Radosevich, J.A., and M. Babich. Fundamentals of antibody-related therapy and diagnostics. Drugs of Today 45(3):199-211, 2009.

1. Vesper, B.J., Jawdi, A., Altman, K.W., Haines III, G.K., Tao, L. and J.A. Radosevich. The Effect of Proton Pump Inhibitors on the Human Microbiota.  Current Drug Metabolism 10(1):84-89, 2009.

110.  Altman, M.B., Vesper, B.J., Smith, B.D., Stinauer, M.A., Pelizzari, C.A., Aydogan, B., Reft, C.S., Radosevich, J.A., Chmura, S.J., and J.C. Roeske. Characterization of a Novel Phantom for Three-Dimensional In Vitro Cell Experiments.  Physics in Medicine and Biology 54(5):N75-N82, 2009.

111.  Altman, K.W. and J.A. Radosevich. Unexpected Consequences of Proton Pump Inhibitor Use. Laryngascope. 141:564-566, 2009.

112.  Radosevich, J. A., Elseth, K. M., Vepser, B. J., Targan G., and G. K. Haines III. Long-Term Adaptation of Lung Tumor Cell Lines with Increasing Concentrations of Nitric Oxide Donor. The Open Lung Cancer Journal 2:35-44, 2009.

1.   Trivedi, E. R., Vesper, B.E., Weitman, H., Ehrenberg, B., Barrett, A.G.M., Radosevich, J.A., and B. M., Hoffman. Chiral Porphyrazines as Optical Agents for the Diagnosis and Treatment of Cancer. Photochemistry and Photobiology 86:410-417, 2010.

114.   Vesper, B.J., Elseth, K.M., Tarjan, G., Haines III, G.K., and J.A. Radosevich. Long-Term Adaptation of Breast Tumor Cell Lines to High Concentrations of Nitric Oxide. Tumor Biology 31:267-275, 2010.

115.   Paradise, W.A., Vesper, B.J., Goel, A., Waltonen, J.D., Altman, K.W., Haines, G.K., and J.A. Radosevich. Nitric Oxide: perspectives and Emerging Studies of a Well Known Cytotoxin. Inter. J. Mol. Sci. 11:2715-45, 2010.

116.   Song, Y., Zong, H., Trivedi, E., Vesper, B., Waters, E., Barrett, A., Radosevich, J., Hoffman, B., and T. Meade. Synthesis and Characterization of New Porphyrazine- GD (III) Conjugates as Multimodal MR Contrast Agents. Bioconjugate Chem. 21:2267-75, 2010.

117.   Rubinstein, P.G., Lindgren, V., Setty, S., Yao, M., Pytynia, K., Radosevich, J.A., Kadkol, S.S., and L.E.  Feldman. Durable Complete Remission Induced by Cetuximab Monotherapy in an HIV Infected Patient with Recurrent Squamous Cell Carcinoma of the Head & Neck. J. Clin. Onoc. 29:222-225, 2010.

118.   Yarmolyuk, Y., Vesper, B.J., Paradise, W.A., Elseth, K.M., Tarjan, G., Haines III, G.K., and J.A. Radosevich. Part I. Development of a Model System For Studying Nitric Oxide in Tumors: High Nitric Oxide-Adapted Head and Neck Squamous Cell Carcinoma Cell Lines. Tumor Biol. 32:77-85, 2010.

119.   Tarjan, G., Haines III, G. K., Vesper, B.J., Xue, J., Altman, M.B., Yarmolyuk, Y., Elseth, K.M., Roeske, J., C., Aydogan, B., and J.A. Radosevich. Part II. Initial Molecular and Cellular Characterization of High Nitric Oxide-Adapted Human Tongue Squamous Cell Carcinoma Cell Lines. Tumor Biol. 32:87-98, 2010.

120.    Yeginer, M., Roeske, J.C., Radosevich, J.A., and B. Aydogan. Linear Accelerator-Based Intensity-Modulated Total Marrow Irradiation Technique for Treatment of Hematological Dosimetric Feasibility Study. Int. J. Radiat. Oncol. Biol. Phys. 79:1256-65, 2010.

121.    Aydogan, B., Yeginer, M., Kavak, G.O., Fan, J., Radosevich, J., and K. Gwe-Ya. Total Marrow Irradiation with RapidArc Volumetric Arc Therapy. Int. J. Radiat. Oncol. Biol. Phys. 81:592-599, 2011.

122.    Paradise, W.A., Vesper, B.J., Babich, M., Colvard, M.D., and J.A. Radosevich. Methods, Processes and Comparative Yield Economics for the Production of Antibodies, Recombinant Proteins. Immuno., Endo. & Metab. Agents in Med. Chem. 11:199-219, 2011.

123.    Altman, K.W., Kinoshito, Y., Tan-Geller, M., Burstein, D., and J. A. Radosevich. Western Blot Confirmation of the H+/K+-ATPase Proton Pump in the Human Larynx and Submandibular Gland. J. Human Larynx and Submandibular Gland. 145:783-788, 2011.

124.    Surucu, M., Yeginer, M., Kavak, G.O., Fan, J., Radosevich, J.A., B. Aydogan. Verification of Dose Distribution For Volumetric Modulated Arc Therapy Total Marrow Irradiation In A Humanlike Phantom. Med. Phys. 39:281-288, 2012.

125.   Onul, A., Elseth, K., de Vitto, H., Paradise, W.A., Vesper, B.J., Tarjan, G., Haines III, G.K., Rumjanck, F. D., and J.A. Radosevich. Long-term Adaptation of The Human Lung Tumor Cell Line A549 to Increasing Concentrations of Hydrogen Peroxide. Tumor Biol. 33:739-748, 2012.

126.  Onul, A. Colvard, M., Paradise, W.A., Elseth, K.M., Vesper, B.J., Gouvas, E., Platt, F.J., Pestle, W., and  J.A. Radosevich. Development of a New Method Based On Antigen Destruction As A Measure of Tissue Damage. J. Histochem. Cytochem. 60: 683-693, 2012.

127.  Vesper, B.J., Onul, A., Haines III, G.K., Targan, G., Xue, J., Elseth, K.M., Aydogan, B., Altman, M.B., Roeske, J.C., Paradise, W.A., De Vitto, H., and J. A. Radosevich. Part I. Molecular and Cellular Characterization of High Nitric Oxide – Adapted Human Breast Adenocarcinoma Cell Lines. Tumor Biol. 34:203-214, 2013.

128.  De Vitto, H., Mendonca, B.S., Elseth, K.M., Vesper, B.J., Portari, E.A., Gallo, C.V.M., Paradise, W.A., Rumjanek, F.D., and J. A. Radosevich. Part II. Mitochondrial Mutational Status of High Nitric Oxide Adapted Cell Line BT-20 (BT-20-HNO) As It Relates To Human Primary Breast Tumors. Tumor Biol. 34:337-47, 2013.

129.  De Vitto, H., Mendonca, B.S., Elseth, K.M., Onul, A., Xue, J., Vepser, B.J., Gallo, C.V.M., Rumjanek, F.D., Paradise, W.A., and J. A. Radosevich. Part III. Molecular Changes Induced By High Nitric Oxide Adaptation in Human Breast Cancer Cell Line BT-20 (BT-20-HNO): A Switch From Aerobic to Anaerobic Metabolism. Tumor Biol.  34:403-13, 2013.

130.  Breskey, J.D., Lacey, S.E., Vesper, B.J., Paradise, W.M., Radosevich, J.A., and M.D. Colvard. Photodynamic Therapy: Occupational Hazards and Preventative Recommendations for Clinical Administration By Healthcare Providers. Photomedicine and Laser Surgery 31:398-407, 2013.

131.  Aqil, M., Elseth, K.M., Vesper, B.J., Aydogan, B., Xue, J., and J.A. Radosevich. Part I – Mechanism of Adaptation: High Nitric Oxide Adapted A549 Cells Show Enhanced DNA Damage Response And Activation Of Antiapoptic pathways. Tumor Biol. 35: 2403-2415, 2014.

132.   Aqil, M., Deliu, Z., Elseth, K.M., Shen, G., Xue, J., and J.A. Radosevich. Part II – Mechanism of Adaptation: A549 Cells Adapt To High Concentration of Nitric Oxide Through Bypass of Cell Cycle Checkpoints. Tumor Biol.  35:2417-2425, 2014.

133.  Aqil, M., Elseth, K.M., Arjunakani, A., Nebres, P., Amegashie, C.P., Desai, P.B., Thanki, D.H., and J.A. Radosevich. A549 Cells Adapted To High Nitric Oxide Show Reduced Surface CEACAM Expression and Altered Adhesion and Migration Properties. Tumor Biol. 36:1871-1879, 2014.

134.   Bassiony, M.A., Aqil, M., Khalili, M., Radosevich, J.A., and Heba M. Elsabaa. Tobacco Consumption and Oral, Pharyngeal and Lung cancers. The Open Can. J. 8:1-11, 2015.

135.  De Vitto, H., Perez-Valencia, J., and J.A. Radosevich. Glutamine at Focus: Versatile Roles in Cancer. Tumor Bio 37(2):1541-58. 2016.

136.   Mandal, C.C., Sharma, A., Panwar, M.S., and J.A. Radosevich.  Is Cholesterol a Mediator of Cold-Induced Cancer?  Tumor Bio. 37:9635–9648, 2016.

137.  Sharma, T., Radosevich, J.A., Pachori, G., C.C. Mandal. A Molecular View of Pathological Microcalcification in Breast Cancer. Tumor Bio. 21(1-2):25-40, 2016.

138.  Aydogan, B., and J.A. Radosevich. Tumor Specific Daily Dose Fractionation Schedules May Improve Radiotherapy. Radiotherapy and Oncology. 2016.

139.  Budyn, E., Bhogie, S., Mistry, G., Vesper, B., Lacey, S., Radosevich, J.A., and M. Colvard. Identification of Cell Thermal Microenvironment in Porcine Skin During Laser Cauterization. Computer Methods in Applied Mechanics and Engineering. 314:19-45, 2016.

140.  Aqil, M., Deliu, Z., Tauseet, M., Bassiony, M., Verma, R., Kim, K., and J.A. Radosevich. A549 Cells Adapted to High Nitric Oxide Show Increased HIF-1-Alpha Expression and Reduced Oxidative Stress. Tumor Biology. 2016.

141.  Deliu, Z., Tamas, T., Aqil, M., Bassiony, M., and J.A. Radosevich. Expression of Cross-Tolerance to a Wide Range of Conditions in a Human Ling Cancer Cell Line After Adaptation to Nitric Oxide. Tumor Biology. 1:1-10, 2017.

142.  Sharma, A., Sharma, T., Panwar, M.S., Sharma, D., Bundel, R., Hamilton, R.T., Radosevich, J.A., and C. C. Mandal. Colder Environments Are Associated with a Greater Cancer Incidence in the Female Population of the United States. Tumor Biol. 39:1-12, 2017

143. Radosevich, J.A. and M. Babich. Labyrinthin, the Tumor Marker Recognized by MCA 44-3A6: A case for Pan-Tumor Markers as targets to Treat Cancer, OncoTarg. and Therapy, (12:9351-9354, 2019).

144.  Demiran, B., Yucel, B., Kaya, A., and J.A. Radosevich.  Epigenetic Alterations in High Nitric Oxide-Adapted Head and Neck Squamous cell Carcinoma Cell lines. Cancer Sci. Res. 2:1-5, 2019.

145.  Demiran, B., Yucel, B., and J.A. Radosevich. DNA Methylation in High Nitric Oxide-Adapted Human Breast Cancer Cell Lines. In Vivo In Vivo. In Vivo 34:169-176, 2020.

146.  Sharma, T., Radosevich, J.A., and C.C. Mandal. Dual role of microRNAs in autophagy of colorectal cancer. Endocrine, Metabolic & Immune Disorders – Drug Targets. (In Press, 2020)

BOOK CHAPTERS:

1.   Radosevich, James A., Ma, Yixing, Weitzman, Sigmund A., Steven T. Rosen. Non-Small

Cell Lung Cancer Antigens.  In:  Lung Biology in Health and Disease. L’Enfant, C.,

Abrams, P., Rosen, S.T. (Eds.), p237-253, 1988.

2.   Radosevich, James A., Lee, Inchal, Gould, Victor E., and Steven T. Rosen. Monoclonal

Antibody Assays For Lung Cancer.  In:  In Vitro Diagnosis of Human Tumors Using

Monoclonal Antibodies.  H.Z. Kupchik, Noel Rose (Ed.) Immunology Series.  Marcel

Dekker, p101-119, 1988.

3.   Rosen, Steven T., Radosevich, James A. and John Gruhn.  The Biology of Lung Cancer.

In:  The History of Lung Cancer.  J.G. Gruhn (Ed.)  Grune and Stratton. p35-54, 1988.

4.   Rosen, Steven T. and James A. Radosevich.  Biology of Lung Cancer. In: Lung Cancer.

Bitran, J.D. and Golumb, H.R. (Ed.)  Grune and Stratton, p240-249, 1988.

5.   Kaplan, Edward H., Goldman-Leikin, Robin E., Radosevich, James A., Zimmer, A.

Michael, and Steven T. Rosen.  Current Status of Monoclonal Antibodies in Cancer

Therapy.  Proceedings of the Sixth Annual Symposium on Geriatrics and Gerontology –

Cancer and Aging. T.V. Zenser and R.M. Coe (Eds), Springer Publishing Co., p86-109,

1989.

6.   Radosevich, J.A., Ritts, R.E., and Rosen, S.T.  Immunology of Human Bronchial Cancer.

In: General Thoracic Surgery. 3rd Ed., T.W. Shield (Ed), Lea & Febiger, p1211-1216,

1989.

7.   Gruhn, J., Radosevich, J.A., and S.T. Rosen. Lung Cancer: Changing Concepts. In:

Advances in Pathology, Vol. 3, Mosby Year Book Publishers, 1990.

8.   Cohn, S.L., Robinson, P.G., Radosevich J.A. and S.T. Rosen. Tumor Markers and

Phenotyping Techniques.  In Adjuncts In Surgery. S. Economous, Ed. 1991.

9.   Robinson, P.G. and J.A. Radosevich. Mediastinal Tumor Markers. In: The Mediastinum.

T.W. Shields (Ed.). Lea and Febiger, 1991.

10.   Radosevich, J., Haines, G.K., Ghadge, G., and B. Thimmappaya. Double-Stranded

RNA-Dependent Protein Kinase (P-68) As A Differentiation Marker In Human Lung

Cancer. In: Lung Cancer Differentiation. Lung Biology in Health and disease. L’Enfant,

C., Bernal, S., and Baylin, S. (Eds.). Marcel Dekker, 1992.

11.   Radosevich, J.A., Combs, S.G. and S.T. Rosen.  Immunohistochemical Analysis of

Lung Cancer Differentiation Markers. In: Lung Cancer Differentiation. Lung Biology in

Health and disease. L’Enfant, C., Bernal, S., and Baylin, S. (Eds.). Marcel Dekker, 1992.

12.   Shambaugh, III, G.E., Metzger, B.E., and J.A. Radosevich. Nutrient Metabolism and

Fetal Brain Development. In: Perinatal Biochemistry. Emilio Herrera and Robert H.

Knoop (Eds.), CRC Press, 1992.

13.   Radosevich, J.A., and Rosen, S.T.  Immunology of Human Bronchial Cancer.  In:

General Thoracic Surgery. 4th Ed., T.W.Shield (Ed), Williams & Wilkins, 1994.

14.   Radosevich, J.A. Immunophenotyping of Lung Cancer. In: General Thoracic Surgery.

4th Ed., T.W.Shield (Ed), Williams & Wilkins, 1994.

15.   Shields, T.W., Robinson, P.G., and Radosevich, J.A. Lung Cancer – Etiology,

Carcinogenesis and Pathology. In: General Thoracic Surgery. 4th Ed., T.W.Shield (Ed),

Williams & Wilkins, 1994.

16.   Vesper, B.J., Barrentt, A.G.M., Hoffman, B.M., and J.A. Radosevich. Porphyrazine Anti-Tumor

Agents, Clinical Chemistry Research. Eds: B.H. Mitchem & C.L. Sharnham., Nova Science

Publishers, Hauppauge NY, ISBN: 978-1-60692-517-1, 2009.

17.    Altman, K.W., Paradise, W.A, Vesper, B., and James A. Radosevich. Non-Gastric Proton Pumps As An Adjunctive Mechanism For Acid Secretions. In: Effects, Diagnosis and Management of Exrta-esophageal Reflux: A Multi-Disciplinary Approach From World-Renowned Experts In The Field. N. Johnson (Ed)., 2010.

18.   Paradise, W. A.; Altman, K. W.; Vesper, B. J.; Radosevich, J. A. “Systemic Implications in the Pharmacologic Treatment of Gastroesophageal Reflux Disease (GERD).” In: Reflux Disease: Causes, Symptoms, and Treatment.” Nova Science Publishers: New York, 2010.

19.   Xue, J., Vesper, B.J., and J.A. Radosevich. Human Papillomavirus: A Brief Overview. In: HPV and Cancer, J.A. Radosevich (Ed.), Springer Publishers, 2013.

20.   Xue, J., Vesper, B.J., and J.A. Radosevich. Proteins Encoded By The Human Papillomavirus Genome and Their Functions. In: HPV and Cancer, J.A. Radosevich (Ed.), Springer Publishers, 2013.

21.   Xue, J., Vesper, B.J., and J.A. Radosevich. The Life Cycle of Human Papillomavirus. In: HPV and Cancer,  J.A. Radosevich (Ed.), Springer Publishers. 2013.

22.    J.A. Radosevich. Overview of “Head & Neck Cancer: Current Perspectives, Advances, and Challenges.” In: Head & Neck Cancer: Current Perspectives, Advances, and Challenges. J.A. Radosevich (Ed.), Springer Publishers 2013.

23.   Paradise, W.A., and J.A. Radosevich. Viruses and Head & Neck Cancer. In: Head & Neck Cancer: Current Perspectives, Advances, and Challenges. J.A. Radosevich (Ed.), Springer Publishers 2013.

24.    Bassiony, M., Aydrogan, B., and J.A. Radosevich. Diagnostic Imaging Considerations. In: Head & Neck Cancer: Current Perspectives, Advances, and Challenges. J.A. Radosevich (Ed.), Springer Publishers 2013.

25.   Paradise, W.A., and J.A. Radosevich. Biological treatments (Antibodies). In: Head & Neck Cancer: Current Perspectives, Advances, and Challenges. J.A. Radosevich (Ed.), Springer Publishers 2013.

26.   Aqil, M. and J.A. Radosevich. Mechanisms of Nitric Oxide Mediated UV Resistance in Solid Tumors. In: UV Radiation: Properties, Effects, and Applications, Nova Scientific Publishers 2014.

27.  Demircan, B., Deliu, Z., Alkoc, O.A. and J.A. Radosevich. The Use of UV Lasers in Fluorescent Activated Cell Sorter Analysis. In: UV Radiation: Properties, Effects, and Applications, Nova Scientific Publishers 2014.

28.  De Vitto, H. Valencia, J.P., and J.A. Radosevich. General View of the Cytoplasmic and Nuclear Features of Apoptosis. In: Apoptosis and Beyond: The Many Ways Cells Die, Wiley Publishers, 2018.

29.  Khalili, M. and J.A. Radosevich. Paraptosis. In: Apoptosis and Beyond: The Many Ways Cells Die, Wiley Publishers, 2018.

30.  Raja, M.K., Chowdhury, J., and J.A. Radosevich. Role of Phospholipase in Cell Death. In: Apoptosis and Beyond: The Many Ways Cells Die, Wiley Publishers, 2018.

31.  Khalili, M. and J.A. Radosevich. Pyronecrosis. In: Apoptosis and Beyond: The Many Ways Cells Die, Wiley Publishers, 2018.

32.   Bassiony, M., Aluko, A.V., and J.A. Radosevich, Immunotherapy and Cancer, Precision Medicine In Oncology. Wiley Publishers. (In Press, 2020).

Books:

1.   J.A. Radosevich. (Ed.) HPV and Cancer. Springer Publishers, 2013.

2.   J.A. Radosevich (Ed.) Head & Neck Cancer: Current Perspectives, Advances, and Challenges. Springer Publishers. 2013.

3.  J.A. Radosevich (Ed.) UV Radiation: Properties, Effects, and Applications. Nova Scientific Publishers. 2014.

4.  J.A. Radosevich (Ed.) Apoptosis and Beyond: The Many Ways Cells Die. (Part I), Wiley Publishers. 2018.

5.  J.A. Radosevich (Ed.) Apoptosis and Beyond: The Many Ways Cells Die. (Part II), Wiley Publishers. 2018.

6.  Aydogan, B. and J.A. Radosevich (Eds). Precision Medicine In Oncology. Wiley Publishers. (In Press, 2020).

ABSTRACTS:

1.   Radosevich, James A. and A. Galsky.  Ion Uptake and Crown-gall Tumor Formation.

Plant physiol. Suppl. 61: 72 (Presented at the American Society of Plant Physiology

Meetings.  Blacksburg, Virginia, 1978.)

2.   Radosevich, James A. and S.L. Barclay.  Membrane Topology of Developmentally

Regulated Antigenic Determinants of Dictyostelium discoideum. (Presented at the

Sigma Xi Graduate Student Research Forum, Chicago, Illinois, 1982.)

3.   Radosevich, James A. and S.L. Barclay.  Partial Characterization of the Glycolipid-Like

Plasma Membrane Components of Dictyostelium discoideum and Polysphondylium

violaceum. (Presented at the International Cellular Slime Mold Conference, Hartford,

Connecticut,1982).

4.   Radosevich, James A. and S.L. Barclay. Characterization and Topology of Glycolipid-Like

Components of Dictyostelium discoideum and Polysphondylium violaceum. (Presented at

the Annual Meeting of the American Society of Microbiology, New Orleans, Louisiana,

1983.)

5.   Radosevich, James A. and S.L. Barclay.  Development of a New Hydrophobic Stain for

Polyacrylomide Gels: The Hydrophobic Association Stain. (Presented at the Annual

Meeting of the American Association for the Advancement of Science, Detroit, Michigan,

1983.)

6.   Radosevich, James A. and S.L. Barclay.  Developmentally Regulated Plasma Membrane

Components of Dictoyostelium discoideum: Identification of Peripheral and Integral

Proteins. (Presented at the Midwest Regional Developmental Biology Conference, W.

Lafayette, Indiana, 1983.)

7.   Radosevich, James A. and S.L. Barclay.  Developmentally Regulated Cytoskeletal

Components of Dictyostelium discoideum.  (Presented at the Midwest Regional

Developmental Biology Conference, W. Lafayette, Indiana, 1983.)

8.   Radosevich, James A., 1983.  Characterization of Dictyostelium discoideum Plasma

Membrane Components.  (Dissertation Abstracts International, Volume 45, Number

02, 1984.)

9.   Radosevich, James A., Radosevich, E.A. and S.L. Barclay.  A Mathematical Model

Which Predicts the Molecular Composition and Structure of the Glycolipid-Like

Components of Dictyostelium discoidium and Polysphondylium violaceum.(Presented at

the Annual Meeting of the American Society of Microbiology, St. Louis, Missouri, 1984.)

10.  Radosevich, James A., Jung, L.K.F., Ma, Y., and S.T. Rosen. A Monoclonal Antibody

Directed Against A Cell Surface Antigen On Human Adenocarcinoma of the Lung.

(Presented at the Midwest Section of the American Federation For Clinical Research,

Chicago, Illinois, 1984.)

11.  Radosevich, J.A., Lambiase, E.A., Ma, Y., Salwen, H. and S.T. Rosen. Monoclonal

Antibody 461D8 Reacts with A Cell Surface Component On Human Adenocarcinoma

of the Lung.  (Presented at The Fourth Annual Congress For Hybridoma Research,

San Francisco, California, 1985.)

12.  Zimmer, A.M., Rosen, S.T., Spies, S.M., Radosevich, J.A. and D.I. Webber.

Radioimmunoscintigraphy of Human Lung Adenocarcinoma with 131I Tumor-Specific

Monoclonal Antibody.  (Fourth Annual Congress for Hybridoma Research, San

Francisco, California, 1985.)

13.  Rosen, S.T., Runge-Morris, M., Lee, I.C., Ma, Y., Salwen, H., Zimmer, A.M., Gould,

V.E. and J.A. Radosevich.  A Monoclonal Antibody Which Reacts with A Cell Surface

Antigen on Human Adenocarcinoma of The Lung.  (Annual Meeting of The American

Association for Clinical Research, Houston, Texas, 1985.)

14.  Radosevich, J.A., Koehler, R.R. and G.E. Shambaugh.  Circulating Factors During

Maternal Starvation May Alter Development of Acetylcholinesterase In Fetal Rat Brain.

(Presented at the National American Federation for Clinical Research, Washington, D.C.,

1985.)

15.  Lee, I., Gould, V.E., Radosevich, J.A., Ma, Y. and S.T. Rosen. Immunohistochemical

Staining of Various Lung Carcinoma Types with Monoclonal Antibody 44-3A6

(National American Federation for Clinical Research. Washington, D.C., 1985.)

16.  Radosevich, J.A., Ma, Y., Salwen, H.R., Jung, L.K.F., Combs, S.G., Lee, I., Gould,

V.E., and S.T. Rosen.  Characterization of Lung Cancer Cell Surface Antigens Using

Monoclonal Antibodies as Specific Probes. (Presented at the IV World Conference on

Lung Cancer, Toronto, Canada, 1985.)

17.  Lee, I., Radosevich, J.A., Rosen, S.T., Ma, Y. and V.E. Gould. Immunohistochemical

Staining of Various Lung Carcinomas with Monoclonal Antibody 44-3A6.  (IV World

Conference on Lung Cancer, Toronto, Canada, 1985.)

18.  Zimmer, A.M., Rosen, S.T., Spies, S.M., Radosevich, J.A., Webber, D.I. and J.M.

Kazikiewicz.  Radioimmunoscintigraphy of Human Lung Adenocarcinoma with I-131

Tumor-Specific Monoclonal Antibody. (Annual Meeting of the Society of Nuclear

Medicine, Chicago, Illinois, 1985.)

19.  Shambaugh, G.E., Koehler, R.R. and J.A. Radosevich.  Nutritional Impact on Fetal Brain

Development: A New In Vitro Model Which Parallels in Vivo Responses. (Midwest

Section of the American Federation for Clinical Research, Chicago, Illinois, 1985.)

20.  Combs, S.G., Rosen, S.T., Ma, Y., Lee, I., Gould, V.E. and J.A. Radosevich.

Immunohistochemical Detection of an Antigenic Determinant Expressed on Select

Human Adenocarcinomas. (Midwest Section of the American Federation for Clinical

Research, Chicago, Illinois, 1985.)

21.  Rosen, S.T., Gould, V.E., Salwen, H., Lee, I., Bauer, K., Marder, R., Anderson, R., Kies,

M., Moll, M., Franke, W., and J.A. Radosevich. Characterization of a Neuroendocrine

Skin Carcinoma Cell Line: In Vitro Similarities with Bronchopulmonary Neuroendocrine

Carcinomas. (Midwest Section of the American Federation for Clinical Research,

Chicago, Illinois, 1985.)

22.  Banner, B.F., Gould, V.E., Lee, I., Ma, Y., Radosevich, J.A. and S.T. Rosen. Detection

of Phenotypic Exocrine Features in Large Cell Undifferentiated Carcinomas of the Lung

with MCA 44-3A6. (International Academy of Pathology, New Orleans, Louisiana, 1986.)

23.  Lee, I., Radosevich, J.A., Ma, Y., Chejfec, G., Rosen, S.T. and V.E. Gould.Immunohisto-

chemical Analysis of Pleural Mesotheliomas With Monoclonal Antibodies 44-3A6 and

624A12. (International Academy of Pathology, New Orleans, Louisiana, 1986.)

24.  Gould, V.E., Rosen, S.T., Salwen, H.R., LeBeau, M.M., Lee, I., Bauer, K.D., Marder,

R., Moll, R., Franke, W.W. and J.A. Radosevich. Establishment and Characterization of a

Neuroendocrine Skin Carcinoma Cell Line. (International Academy of Pathology, New

Orleans, Louisiana, 1986.)

25.  Combs, S.G., Lee, I., Gould, V.E., Ma, Y., Rosen, S.T. and J.A. Radosevich.

Immunohistochemical Detection of The Antigenic Determinant Recognized By The

Monoclonal Antibody 44-3A6 on Select Human Adenocarcinomas.  (International

Academy of Pathology, New Orleans, Louisiana, 1986.)

26.  Shambaugh, G.E., Koehler, R.R. and J.A. Radosevich.  Nutritional Impact on Fetal Brain

Development:  A New In Vitro Model Which Parallels In Vivo Responses. (FASEB, St.

Louis, Missouri, 1986.)

27.  Shambaugh, G.E., Koehler, R.R., and J.A. Radosevich.  Circulating Factors May

Modulate Acetylcholinesterase Levels In Fetal Rat Brain During Maternal Starvation.

(The Endocrine Society Annual Meeting.  Anaheim, California, 1986.)

28.  Zimmer, A.M., Radosevich, J.A., Kazikiewicz, J.M., Spies, S.M., Rosen, S.T., Johnson,

D.K. and R.L. Vessella. Pharmacokinetics and Radioimmunoimaging of Radiolabeled

Monoclonal Antibodies to Human Lung Adenocarcinoma.  (Society of Nuclear Medicine

33rd Annual Meeting, Washington, D.C., June 1986.)

29.  Radosevich, J.A., Mulshine, J.L., Zimmer, A.M. and S.T. Rosen. Monoclonal Antibodies

In Immunodiagnosis and Immunotherapy of Human Lung Cancer. (Presented at the 14th

International Cancer Congress, Budapest, Hungary, 1986.)

30.  Radosevich, J.A., Lee, I., Ma, Y., Gould, V.E., Carney, W.P. and S.T. Rosen.

Comparison of the Expression of Normal and Mutated ras p21 Oncogene Products

in Human Lung Neoplasms Detected by the Monoclonal Antibodies RAP-5 and DWP.

(Presented at the Midwest Section of the American Federation of Clinical Research,

Chicago, Illinois, 1986.)

1. Ma, Y., Lee, I., Radosevich, J.A., Gould, V.E., Thor, A., Schlom, J., and S.T. Rosen.

Immunohistochemical Analysis of Pulmonary Carcinomas with Monoclonal Antibody

B72.3. (The Midwest Section of the American Federation of Clinical Research,

Chicago, Illinois, 1986.)

32.  Combs, S.G., Radosevich, J.A., Ma, Y., Lee, I., Gould, V.E., Thor, A., Schlom, J.,

and S.T. Rosen.  RAP-5 Immunohistochemical Detection of the Expression of ras

Oncogene p 21 In Human Fetal Tissues. (The Midwest Section of the American

Federation of Clinical Research, Chicago, Illinois, 1986.)

33.  Lee, I., Radosevich, J.A., Ma, Y., Gould, V.E., Thor, A., Schlom, J. and S.T. Rosen.

Expression of ras Oncogene p21 in Human Lung Carcinomas Detected by Monoclonal

Antibody RAP-5.  (The Midwest Section of the American Federation of Clinical

Research, Chicago, Illinois, 1986.)

34.  Shambaugh, G.E., Koehler, R. and J.A. Radosevich.  Circulating Factors May Contribute

to Adaptive Responses in Fetal Rat Brain During Maternal Starvation. (The Midwest

Section of the American Federation of Clinical Research, Chicago, Illinois, 1986).

35.  Lee, I., Radosevich, J., Carney, W., Ho, M., Rabin, H., Ma, Y., Warren, W., Rosen, S.

and V. Gould.  Immunohistochemical Analysis of Pulmonary and Pleural Neoplasms

Using Monoclonal Antibody 47D10.  (The International Academy of

Pathology, Chicago, Illinois, 1987.)

36.  Lee, I., Radosevich, J., Carney, W., Rabin, H., Ma, Y., Scholm, I., Rosen, S. and V.

Gould.  Immunohistochemical Detection of Unaltered and Mutated ras Oncogene

Products in Pulmonary Neoplasma.  (The International Academy of Pathology,

Chicago, Illinois, 1987.)

37.  Curruthers, Mary M., Kabat, William J., Ma, Yixing, Rosen, Steven T. and James A.

Radosevich.  Monoclonal Antibodies Directed Against Cell Surface Antigens of Vibrio

vulnificus.  (American Society of Microbiology, Atlanta, Ga., 1987.)

38.  Piehl, M.R., Lee, I., Ma, Y., Warren, W.H., Radosevich, J.A., Rosen, S.T. and V.E.

Gould.  Subsets of Pulmonary Large Cell Undifferentiated Carcinomas Defined

Immunohistochemically.  (The International Academy of Pathology, Chicago,

Illinois, 1987.)

39.  Combs, S., Hidvegi, D., Ma, Y., Rosen, S.T., and J.A. Radosevich. Evaluation of a

Pleomorphic Adenocascinoma of the Pancreas With The Monoclonal Antibody 44-3A6.

(The 35th Annual Meeting of the American Society of Cytology, San Francisco,

California, 1987.)

40.  Barch, D., Radosevich, J., Carney, W., and P. Iannaccone. Evidence Supporting

a G->A Transition at Position 34 in H-ras-1 in Methylbenzylnitrosamine Esophageal

Tumorigenesis.  (The American Society of Cell Biology, St. Louis, Missouri, 1987.)

41.  Keep, J.C., Benson, III, A.B., Ma, Y., Carney, W.P., Rosen, S.T.and J.A. Radosevich.

Immunohistochemical Analysis of Colon Adenocarcinoma with Monoclonal Antibody

47010. (The American Federation of Clinical Research, Chicago, Illinois, 1987.)

42.  Robinson, P.G., Radosevich, J.A., Stahel, R.A., Waibel, R., Ma, Y., Gould, V.E., and

S.T. Rosen.  Immunohistochemical Analysis of Human Pulmonary Carcinoma Using

SWA20.  (The American Federation of Clinical Research, Chicago, Illinois, 1987.)

43.  Shambough III, G.E., Koehler, R.R., and J.A. Radosevich. Mechanisms Underlying the

Adaptive Responses of Fetal Brain to Maternal Starvation. (The American Federation

of Clinical Research, Chicago, Illinois, 1987.)

44.  Shambaugh III, G.E., Koehler, R.R., and J.A. Radosevich. Altered Development of Fetal

Brain Cells by Adult Serum: The Impact of Starvation. (FASEB, San Diego, California,

1988.)

45.  Kaplan, E.H., Zimmer, A.M., Lurain, J., Miller, D.S., Kazikiewicz, J.M., Goldman-Leikin,

R.E., Manzel, L., Spies, S.M., Spies, W.G., Radosevich, J.A., Hidvegi, D., and S.T.

Rosen.  Intraperitoneal (IP) Infusion of 131I-Labeled Murine Monoclonal Antibody

(B72.3) for Radioimaging (Dx) and Radioimmunotherapy (Tx) of Advanced Ovarian

Cancer. (American Association of Clinical Research, New Orleans, Louisiana, 1988.)

46.  Zimmer, A.M., Kaplan, E.H., Lurain, J., Miller, D.S., Kazikiewicz, J.M., Goldman-Leikin,

R.E., Radosevich, J.A., Manzel, L., Spies, W.G., Hidvegi, D., Silverstein, E.A., Spies,

S.M., and S.T. Rosen. Pharmacokinetics of 131I-Labeled B72.3 in Patients with Advanced

Ovarian Cancer Following Intraperitoneal Infusion. (The Society of Nuclear Medicine 35th

Annual Meeting, San Francisco, California, 1988.)

47.  Robinson, P.G., Radosevich, J.A., Stahel, R.A., Waibel, R., Ma, Y., Gould, V.E.,

and S.T. Rosen.  Detection of the Antigen Recognized by the Monoclonal Antibody

(MCA) SWA20 In Human Pulmonary Neoplasms.  (Fifth World Conference on Lung

Cancer, Interlaken, Switzerland, 1988.)

48.  Radosevich, J.A., Robinson, P.G., Rittmann-Grauer, L.S., Wilson, B., Leung, J.P.,

Ma, Y., Maminta, L., Warren W., Gould, V.E., and S.T. Rosen. Immunohistochemical

Analysis of Pulmonary Carcinomas with the Monoclonal Antibody (MCA) HYB612

Directed Against a Multiple Drug Resistance Related Antigen. (Presented at the Fifth

World Conference on Lung Cancer, Interlaken, Switzerland, 1988.)

49.  Radosevich, J.A., Ma, Y., Waibel, R., Maminta, L., Stahel, R.A., and S.T. Rosen. Partial

Purification and Characterization of the Antigen recognized by the monoclonal antibody

(MCA) 44-3A6 from the Human Lung Adenocarcinoma (AC) Cell Line A549. (Presented

at the Fifth World Conference on Lung Cancer, Interlaken, Switzerland, 1988.)

50.  Gould, V.E., Piehl, M.R., Radosevich, J.A., Warren, W.H., Ma, Y., and S.T. Rosen.

Exocrine and Neuroendocrine Subsets of Large Cell Lung Carcinomas Identified by

Immunohistochemistry.  (Fifth World Conference on Lung Cancer, Interlaken,

Switzerland, 1988.)

51.  Keep, J.C., Benson, A.B., Ma, Y., Rosen, S.T., Radosevich, J.A. and Carney W.P.

Immunohistochemical Phenotyping of Colorectal Adenocarcinmas With Five Monoclonal

Antibodies (The American Society of Clinical Pathologist Annual Meeting, Las Vegas,

Nevada, 1988.)

52.  Lo Cicero III, J., Spies, W.G., Rosen, S.T., Zimmer, A.M., Robinson, P.G., Radosevich,

J.A., Kaplan, E.H., Canade, A.B., Manzel, L., Spies, S.M., and Maguire, R.T.

Preoperative Radionuclide Monoclonal Antibody (MCA) Imaging of Lung Cancer. (Fifth

World Conference on Lung Cancer, Interlaken, Switzerland, 1988.)

53.  Spies, W.G., Zimmer, A.M., Robinson, P.G., LoCicero, J., Radosevich, J.A., Kaplan,

E.H., Canade, A.B., Manzel, L., Spies, S.M., Maguire, R.T., and S.T., Rosen.

Monoclonal Antibody Imaging Using In-III-Labeled B72.3 In Human Non-Small Cell

Lung Carcinoma (NSCLC). (The Society of Nuclear Medicine 35th Annual Meeting, San

Francisco, California, 1988).

54.  Robinson, P.G., Eggena, D.W., Koch, A.E., and J.A. Radosevich. Immunohistochemical

Analysis of Iron Containing Tissues In Combination with a Modified Prussian Blue Stain:

Clarification of Possible False Positive Staining. (The American Federation of Clinical

Research, Chicago, Illinois, 1988.)

55.  Lo Cicero,III, J., Peplinski, G.R., Radosevich, J.A., Rosen, S.T., and L.L. Michaelis.

Dose Response Variation to Photodynamic Therapy of In Vitro Human Lung Cancer Cell

Lines. (American Association of Clinical Research, San Francisco, California, 1989.)

56.  Koukoulis, G.K., Radosevich, J.A., Rosen, S.T., and V.E. Gould. Immunocytochemical

Study of Pulmonary and Pleural Tumors With Monoclonal Antibodies (MAbs) B72.3 and

CSLEX-1. (The International Academy of Pathology, San Francisco, California, 1989.)

57.  Shambaugh, G.E., Koehler, R.R., and J.A. Radosevich. Maternal Serum Inhibits Fetal

Brain Cell Growth In Vitro: Implications For Development. (FASEB, New Orleans,

Louisiana, 1989.)

58.  Peplinski, G.R., LoCicero, J., Radosevich, J.A., Rosen, S.T., and L.L. Michaelis.

Response of Human Lung Cancer Cell Lines In Vitro To Photodynamic Therapy.

(Midwest Student Medical Research Forum, Omaha, Nebraska, 1989.)

59.  Benson, III, A.B., Rosen, S.T, Salwen, H., Goldman-Leikin, R., Radosevich, J., Gilyon,

K., Duda, R., Kies, M., and M. Hanna. A Pilot Study of Active-Specific Immunotherapy

With Autologous Tumor Cell (ATC)-BCG Vaccine and 5-Fluorouracil (5-FU) In

Metastic Colorectal Carcinoma (CRC). (American Association of Clinical Research, San

Francisco, California, 1989.)

60.  Koch, A.E., Robinson, P.G., Radosevich, J.A., and R.M. Pope. Immunophenotyping of

Rheumatoid (RA) Synovial Tissue Lymphocytes. (American Rheumatism Association

53rd Annual Scientific Meeting. Cincinnati, Ohio, 1989.)

61.  Zimmer A.M., Kazikiewicz, J.M., Kaplan, E.H., Lurain, J., Miller, D.S., Webber, D.I.,

Patel, B.A., Goldman-Leiken, R.E., Manzel, L., Gilyon, K., Radosevich, J.A., Spies,

W.G., Spies, S.M., and S.T.  Rosen. Human Antimurine Antibody Responses Following

Intraperitoneal Radioimmunotherapy Infusions of Murine Monoclonal Antibodies:

Pharmacokinetic Analysis Following Retreatment. (The Society of Nuclear Medicine 36th

Annual Meeting, St. Louis, Missouri, 1989.)

62.  Zimmer A.M., Kazikiewicz, J.M., Webber, D.I., Patel, B.A., Goldman-Leiken, R.E.,

Radosevich, J.A., Spies, W.G., Spies, S.M., and S.T. Rosen. Stability of Radioiodinated

Monoclonal Antibody Therapy Solutions: In Vitro Storage and Plasma Analysis. (The

Society of Nuclear Medicine 36th Annual Meeting, St. Louis, Missouri, 1989.)

63.  Pensler, J., Langman, C., Radosevich, J., Mangkornanok-Mark, M., Higbee, R., Bauer,

B., Patel, D., and M. Christensen. Estrogen Receptor Density and In Vitro Cellular

Metabolism in Normal and Abnormal Osteoblasts.(Plastic Surgery Research Council,

1989.)

64.  Kwaan, H.C., Radosevich, J.A., Lastre, C., and W. Kabat. Components of the

Fibrinolytic System in Human Tumor Cell Lines. (The XIIth ISTH, 1989.)

65.  Maker, V.K., and J.A. Radosevich. Clinical Implications of Contact Neodymium:YAG

Laser In General Surgery: A Report on 100 Cases. (American College of Surgeons

XXXXth Annual Clinical Congress, Atlanta, Ga., 1989.)

66.  Yew, W.W., Kwan, S.Y.L., Lam, K.C., Chui, K.Y., Hsu, C. and J.A. Radosevich.

Application of Monoclonal Antibody MCA 44-3A6 In The Cytological Subtyping of

Malignant Pleural Effusion and Differential Diagnosis of Exudative Pleural Effusion.

(Australian Thoracic Society Meeting, New Zealand, 1989.)

67.  Maker, V.K., and J.A. Radosevich. In Vitro Evidence That The Contact

Neodymium-Yttrium-Aluminium Garnett (Nd:YAG) Laser Inhibits “Knife”

Metastasis. (The American Federation of Clinical Research, Chicago, Illinois, 1989.)

68.  Radosevich, J.A., Jansson, D.S., Siddiqui, F.S., Piehl, M., Kabat, W., Gruhn, Rosen, S.T.,

and V.E. Gould. Subcellular Localization, Cell Cycle Analysis, and Frequency of

Expression by Metastic Lesions of the Human Adenocarcinoma Antigen Recognized by

The Monoclonal Antibody 44-3A6. (The American Federation of Clinical Research,

Chicago, Illinois, 1989.)

69.  Haines, G.K., Ghadge, G., Combs, S.G., Leslie, W., Thimmappaya, B., and J.A.

Radosevich. Immunohistochemical Detection of Double-Stranded RNA-Dependent

Protein Kinase (P-68) With a Novel Monoclonal Antibody TJ4C4: A Case Report of an

AIDS-Associated Koposi’s Sarcoma Patient Treated With Alpha-Interferon. (The

American Federation of Clinical Research, Chicago, Illinois, 1989.)

70.  Shambaugh, G.E., Koehler, R.R., Clough, D., and J.A. Radosevich. A Gestationally

Derived Growth Inhibitor. (The American Federation of Clinical Research, Chicago,

Illinois, 1989.)

71.  Rizzo, R., Haines, G.K., Pierce, W.H., Pope, R., Radosevich, J.A., and P. Robinson.

Characterization of The Inflammatory Cells In Abdominal Aortic Aneurysms. (23rd

Annual Meeting of The Association for Academic Surgery, Louisville, Kentucky, 1989.)

72.  Ng, Y.K., Radosevich, J.A., Garton, R., Motimoto, R., and P.M. Iannaccone.Expression

of Heat-Shock (hsp70) and ras Genes In Compensatory (Regenerative) Liver Growth: in

situ Mosaic Pattern Analysis In Chimeric Rats. (The Annual Meeting of The ASCB,1989.)

73.  Holets-McCormack, S., Radosevich, J.A., and I. Tribby. Purification Of Human IgM

Monoclonal Antibody. (The First International Hybridoma Conference, Orlando,

Florida, 1990.)

74.  Kwaan, H.C., Radosevich, J.A., and W. Kabat. Components of the Fibrinolytic system in

human tumor cell lines. (American Association of Cancer Research, Washington, DC.

1990.)

75.  Maker, V.K. and J.A. Radosevich. Neodymium-Yttrium-Aluminium Garnett (ND:YAG)

Contact Laser Scalpels Inhibit “Knife” Metastasis In Vitro. (Laser 90 International

Conference, Machester, United Kingdom, 1990.)

76.  Shambaugh, G.E., Koehler, R.R., Clough, D., and J.A. Radosevich. A Circulating Factor

In Late Gestation Inhibits Prolifative Growth In Cerebellar Cells. (The Endocrine Society,

Atlanta, Georgia, 1990.)

77.  Kwaan, H.C., Radosevich, J.A., Cajot, J.-F., Ernst, R., and W. Kabat. Components of the

Plasminogen-Plasmin System In Human Tumor Cell Lines. (Tenth International Congress

on Fibrinolysis, Indianapolis, Indiana, 1990.)

78.  Koch, A.E., Haines, G.K., Rizzo, R.R., Radosevich, J.A., Pope, R.M., Robinson, P.G.,

and W.H. Pearce. Human Abdominal Aortic Aneurysms: Immunophenotypic Analysis

Suggesting an Abarrant Immune Response. (American Federation of Clinical Research,

1990).

79.  Yew, W.W., Kwan, S.Y.L., Wong, P.C., Lam, K.C., Chiu, K.Y., Fu, K.H., and J.A.

Radosevich. Application of MCA 44-3A6 in Classification of Thoracic Tumors Diagnosed

by Percutaneous Transthoracic Needle Biopsies. (International Congress: Joint II Asian-

Pacific Society of Respirology and Indonesian Society of Pulmonologist, Bali, 1990).

80.  Radosevich, J.A., Siddiqui, F.S., Rosen, S.T., and W.J. Kabat. Electron Microscopic

Evaluation and Cell Cycle Analysis of the Human Adenocarcinoma Antigen Recognized

By the Monoclonal Antibody 44-3A6. (Presented at the Second International Workshop

On Small Cell Lung Cancer, London, United Kingdom, 1990).

81.  Radosevich, J.A., Combs, S.G., and S.T. Rosen. Human Fetal Expression of the

Adenocarcinoma Associated Antigen Recognized by the Monoclonal Antibody 44-3A6.

(American Federation of Clinical Research, Chicago, IL, 1990.)

82.  Haines G.K., Ghadge, G., Becker, S., Kies, M., Pelzer, H., Thimmappaya, B., and J.A.

Radosevich. Correlation between the expression of Double-Stranded RNA-Dependent

protein Kinase (P-68) with Squamous Cell Carcinoma Differentiation. (American

Federation of Clinical Research, Chicago, IL, 1990.)

83.  Maker, V.K., Elseth, K.M., and J.A. Radosevich. The Contact

Neodymium-Yttrium-Aluminum (Nd:YAG) Laser Reduces Local Recurrence

of Tumor Growth. (American Federation of Clinical Research, Chicago, IL, 1990.)

84.  Gu, D.S., Shambaugh, G.E., Metzger, B.E., and J.A. Radosevich. Circulating

Growth Factors in the Fetus Alter Brain Cell Growth During Maternal Starvation.

(American Federation of Clinical Research, Chicago, IL, 1990.)

85.  Ng, Y.K., Radosevich, J.A., Bauer, K., and P.M. Iannaccone. Spatiotemperal

Changes of p21 in Hepatocyte Cell Cycle during Liver Regeneration in Normal

and Chimeric Rats. (American Society of Cell Biology, San Francisco, CA, 1990.)

86.  Haines, G.K., Ghadge, G., Thimmappaya, B., and J.A. Radosevich. Expression of the

Protein Kinase P-68 Recognized by the Monoclonal Antibody TJ4C4 in Human Lung

Neoplasms. (Presented at “An International Conference on Lung Cancer,” Boston, 1990.)

87.  Radosevich, J.A., Rosen, S.T., and F.S. Siddiqui. The Human Adenocarcinoma

Associated Antigen Recognized by the Monoclonal Antibody 44-3A6 is a Transmembrane

phosphoprotein. (Presented at “An International Conference on Lung Cancer,” Boston,

1990.)

88.  Langman, C.B., Radosevich, J.A., Higbee, R.H., and J.M. Pensler. Isolation of

Osteoclasts from Membranous Bone of Normal Children Exhibit Nuclear Estrogen and

Progestrone Receptors. (3rd International Workshop On Cells and Cytokines In Bone and

Cartilage, Davos, Switzerland, 1990.)

89.  Shambaugh, III, G.E., Gu, De Sheng, and J.A. Radosevich. Circulating Growth Factors in

the Fetus Alter Brain Cell Growth During Maternal Starvation. (14th International

Diabetes Federation Congress, Washington, D.C., 1991).

90.  Combs, S., Haines, G., Leslie, W., Thimmappaya, B., and J. Radosevich. Immunohisto-

chemical Detection of eIF-2 Alpha Kinase with a Monoclonal Antibody TJ4C4 in

AID associated Kaposi’s Sarcoma. (International Academy of Pathology, Chicago, 1991.)

91.  Shambaugh, III, G.E., Unterman, T.G., Glick, R.A., Kelly, G.C., and J.A. Radosevich.

Neonatal Rat Cerebellar Cells: A Model for study of Production and Regulation of IGF-II

in the CNS. (2nd In ternational IGF Symposium, San Fransico, California, 1991.)

92.  Maker, V.K., Elseth, K.M., and J.A. Radosevich. Control of Local Recurrence

of Breast Cancer Using the Contact Neodymium-Yttrium-Aluminum Garnett

Laser. (American Society for Laser Medicine and Surgery, San Diego, California, 1991.)

93.  Gu, D.S., Shambaugh III, G.E., Metzger, B.E., and J.A. Radosevich. Do Circulating

Growth Factors or Does Altered Cellular Response Play The Principal Role in

Retardation of Fetal Brain Cell Growth During Maternal Starvation. (The Endocrine

Society, Washington D.C., 1991).

94.  Duda, R.B., August, C.Z., Nahrwold, D.L., and J.A. Radosevich. Monoclonal Antibody 44-3A6 As A Tumor Marker For Breast Cancer. (International Surgical Week, Stockholm, Sweden, 1991).

95.  Mittal, B.B., Zimmer, A.M., Sathiaseelan, V., Rosen, S.T., Radosevich, J.A.,

Rademaker, A.W., Pierce, M.C., Webber, D.I., Saini, A., and S.M. Spies. Effects

of Hyperthermia and 131-I anti-CEA monclonal antibody on human colon carcinoma xenografts in nude mice. (Antibody Immunoconj. and Radiopharmaceuticals, 1991).

96.  Saini, A., Mittal, B.B., Zimmer, A.M., Sathiaseelan, V., Rosen, S.T., Radosevich, J.A., Rademaker, A.W., Pierce, M.C., Webber, D.I., and S.M. Spies. Hyperthermia induced enhancement of 131-I radiolabeled monclonal antibodies in colon adenocarcinoma xenografts in nude mice. (Antibody Immunoconj. and Radiopharmaceuticals, 1991).

97.  Shambaugh, G.E., Gu, D., Unterman, T., B. Metzger, and J.A. Radosevich. Restoring

IGF levels in fasted fetal serum enhances fetal brain cell growth. (American Federation of Clinical Research, Chicago, IL, 1991.)

98.  Shambaugh, G.E., Gu, D., Glick, R., Metzger, B., Radosevich, J. A., and T. Unterman.

Can insulin-like growth factor-1 (IGF-I) and binding protein-1 (BP-1) modulate fetal brain

cell growth during maternal starvation. (The Endorcrine Society, San Antonio, Texas,

1992.)

99.  Pensler, J.M., Ledesma, D.F., Hijjawi, J., Radosevich, J.A., and C.B. Langman.

Plagiochephaly: Premature unilateral closure of the coronal suture: A localized disorder of

cellular metabolism. (The Annual Meeting of ASPRS/PSEF/ASMA, Toronto, Ontario,

1992.)

100.  Hijjawi, J., Ledesma, D.F., Radosevich, J.A., and Pensler, J.M. Scaphochephaly– Early

closure of the sagittal suture: A localized metabolic disorder. (The Annual Meeting of

ASPRS/PSEF/ASMA, Toronto, Ontario, 1992.)

101.  Szumel, R., Calujis, R.S., Hidvgi, D.F., and J.A. Radosevich. The monoclonal 44-3A6 as

an adjunct in cytodiagnosis of adenocarcinoma in body fluids. (The Annual Meeting of

the United States and Canadian Academy of Pathology, Atlanta, Georgia, 1992.)

102.  Haines, G.K., Ghadge, G., and J.A. Radosevich. Human fetal expression of the protein

kinase (p68) using the monoclonal antibody TJ4C4. (American Federation of Clinical

Research, Chicago, IL, 1992.)

103.  Kresl, J.J., Meyer, N.A., Potempa, L.A., Chi, C.W., Anderson, B., and J.A. Radosevich.

In vivo evidence that a modified form of human c-reactive protein is an effective agent

which suppresses the growth rate of mouse mammary cell line EMT6 murine breast

cancer. (American Federation of Clinical Research, Chicago, IL, 1992.)

104.  Cajulis, R.S., Hayden, R., Hidvegi, D.F., Duda, R.B., August, C.Z., and J.A. Radosevich.

Monoclonal antibody TJ4C4 as a marker for breast neoplasms. (American Federation of

Clinical Research, Chicago, IL, 1992.)

105.  Pensler, J.M., Ledesma, D.F., Hijjawi, J., Radosevich, J.A., and C.B. Langman.

Plagiochephaly: Premature unilateral closure of the coronal suture: A localized disorder

of cellular metabolism. (Plastic Surgical Forum: Vol. XV, Washington D.C., 1992).

106.  Radosevich, J.A., Bradley, G.S., and K.M. Elseth. Molecular cloning of the human

nag gene which encodes the protein Labyrinthin: The adenocarcinoma tumor

associated antigen detected by the monoclonal antibody 44-3A6. (Presented at

the American Federation of Clinical Research, Chicago, IL, 1993.)

107.  Natarajan, N., Elseth, K.M., Shambaugh III, G.E., and J.A. Radosevich. A rapid

assessment of cell number: Adaptation of the diphenylamine assay to a 96 well assay

format and comparison with the metabolic MTT assay. (American Federation of Clinical

Research, Chicago, IL, 1993.)

108.  Dubreuil, R.R., Souik, P., and J.A. Radosevich. Tumor associated epitopes detected by

workshop antibodies react in similar clusters in Drosophila. (Third International IASLC

Workshop on Lung Tumor and Differentiation Antigens, Zurich, Switzerland, 1993.)

109.  Radosevich, J.A., Bradley, G.S., and K.M. Elseth. Molecular cloning of the human nag

gene: The adenocarcinoma tumor associated antigen (Labyrinthin) detected by the

monoclonal antibody 44-3A6. (Third International IASLC Workshop on Lung Tumor

and Differentiation Antigens, Zurich, Switzerland, 1993.)

110.  Talamonti, M.S., Singh, C., Haines G.K., and J.A. Radosevich. Expression of

the protein kinase p68 recognized by the monoclonal antibody TJ4C4 in human

colon cancer. (The Society of Surgical Oncology, Houston, Texas, 1994.)

111.  Gangopadhyay, A., Chavis, A., Thomas, P., Radosevich, J., and G.K. Haines.

Characterization of monoclonal antibody AGB2 recognizing an antigen expressed

both in canine mammary and human breast carcinomas. (American Association for

Cancer Research, San Fransico, California, 1994.)

112.  Haines, G.K., and J.A. Radosevich. P68 kinase as a new marker for

differentiation in human upper aerodigestive tumors: Clinical and pathological

correlations. (UICC XVI International Cancer Congress, New Delhi, India, 1994.)

113.  Radosevich, J.A., Bradley, G.S., and K.M. Elseth. Cloning of the human nag

gene from a pulmonary adenocarcinoma cell line and expression of the tumor

associated antigen (Labyrinthin) detected by the monoclonal antibody 44-3A6.

(UICC XVI International Cancer Congress, New Delhi, India, 1994.)

114.  Shambaugh III, G., Natarajan, N., Radosevich, J., and T. Unterman. Nutritional

insult in the neonatal cerebellum: Alterations in circulating and tissue levels of

IGF-I and IGF binding proteins (IGFBPs). (The annual meeting of the Endocrine

Society, Anaheim, California, 1994.)

115.   Shambaugh III, G., Natarajan, N., Radosevich, J.A., and M.L. Davenport. Neonatal

caloric deficiency and recovery: Serum and tissue IGFs and their impact on cerebellar

growth. (The Central Society For Clinical Research, Chicago, Illinois, 1994.)

116.  Haines G.K., Cajulis, R.S, Hayden, R.T., Duda, R.B., and J.A. Radosevich. Breast

carcinoma is resistant to the antiproliferative and pro-differentiation effects of p68.

(The Midwest American Federation For Clinical Research, Chicago, Illinois, 1994.)

117.  Radosevich, J.A., Elseth, K.M., Bradley, G.S., and G.K. Haines. pH modulates the

expression of Labyrinthin – The human adenocacinoma marker detected by the

monoclonal antibody 44-3A6. (Presented at the Midwestern American Federation

For Clinical Research, Chicago, Illinois, 1994.)

118.  Radosevich, J.A., Elseth, K.M., and G.S. Bradley. Molecular analysis of Labyrinthin: The

cell surface adenocarcinoma marker recognized by the monoclonal antibody 44-3A6.

(Presented at the International Symposium: Cancer Vaccines, New York, New York,

1994.)

120.  Haines, G.K., Zielinski, M., Brown, T., Panos, R.J., Leyland, J., Becker, S., Kies, M.,

Pelzer, H., and J.A. Radosevich. P68 and PCNA are inversely distributed in squamous

cell carcinoma of the head and neck. (International Academy of Pathology Annual

Meeting, Toronto, Canada, 1995.)

121.  Bentz, B.G., Haines, G.K., vonSchlegell, A.S., Elseth, K.M., Hanson, D.G., and J.A.

Radosevich. Monoclonal antibody 44-3A6 localization of Labyrinthin in salivary gland

neoplasia. (Midwestern American Federation For Clinical Research, Chicago, Illinois,

1995.)

122.  Bentz, B.G., Haines III, G.K., Hanson, D.G., and J.A. Radosevich. Head and neck

squamous cell carcinoma expresses a spectrum of constitutive nitric oxide synthase.

(Fourth International Metting: Biology of nitric oxide, Amelia Island, Florida, 1995.)

123.  Radosevich, J.A., Bradley, G.S., and K.M. Elseth. Epitope mapping of the

adenocarcinoma related monoclonal antibody 44-3A6 on Labyrinthin. (Presented at The

XXIII Meeting of the International Society for Oncodevelopmental Biology and

Medicine, 1995.)

124.  Barnes M.N., Bentz, B., Radosevich, J.A., Huang, C.F., Lurain, J.R., and G.K. Haines,

III. Correlation of the expression of double-stranded RNA-dependent protein kinase

(p68) with differentiation in endometrial carcinoma. (National Meeting of SGO, 1995.)

125.  Bentz, B.G., Haines III, G.K., vonSchlegell A.S., Elseth, K.M., Hanson, D.G., and J.A.

Radosevich. Labyrinthin expression in salivary gland neoplasia. (The American

Laryngological, Rhinological and Otological Society Annual Meeting, Grand Cypress,

Orlando, Florida, 1996.)

126.  Bentz, B.G., Haines III, G.K., Hanson, D.G., and J.A. Radosevich. Prognostic

significance of constitutive nitric oxide synthase in salivary gland neoplasia.

(4th International Conference on Head and Neck Cancer, Toronto, Canada, 1996.)

127.  Radosevich, J.A., Haines III, G.K., Motie, M., Crump, B.L., Schaul, K.W., Kolb, K., and

L.A. Potempa. Immunohistochemical detection of epitopes expressed on CRP and

modified-CRP (i.e.neo-CRP) in human normal and diseased tissues. (Presented at

FASEB, New Orleans, Louisiana, 1996.)

128.  Radosevich, J.A., Elseth, K.M., G.K. Haines, III. Labyrinthin expression is induced by

serum starvation and heat shock in A549 cells. (Presented at the Midwest AFCR

Meetings, Chicago, Illinois, 1996.)

129.  Haines III, G.K., Zielinski, M., Brown, T., Leyland, J., and J.A. Radosevich. Expression

of topoisomerase II in squamous cell carcinoma of the head and neck. (Midwest AFCR

Meetings, Chicago, Illinois, 1996.)

130.  Radosevich, J.A., Elseth, K.M., and G.K. Haines III. Heat shock and serum starvation

induce Labyrinthin expression in A549 cells. (Presented at Cancer Vaccines 1996, New

York, New York, 1996.)

131.  Radosevich, J.A., Elseth, K.M., and G.K. Haines, III. Anti-sense expression of

Labyrinthin in A549 cells results in contact inhibition and reduced growth rate.

(Presented at ISOBM-96, San Diego, California, 1996.)

132.  Potempa, L.A., Murphy, R., Radosevich, J.A., Anderson, B., Kresl, J.J, and B. Chan.

Biological activity and clinical safety of human modified C-reactive protein, an active new

agent against cancer. (Third Hong Kong International Cacner Congress and Seventh

International EBV Symposium, Hong Kong, 1996.)

133.  Potempa, L.A., Motie, M., Murphy, R., Kabat, W., Yogev, R., Radosevich, J.A., Vaith,

P., and B. Chan. In vitro studies of recombinant human modified C reactive protein, an

active new agent against HIV disease. (Hong Kong AIDS Conference, Hong Kong,1996.)

134.  Bentz, B.G., Barnes, M.N., Haines, G.K., Lurain, J.R., Hanson, D.G., and J.A.

Radosevich. Constitutive Nitric oxide synthase is diffusely expressed in endometrial

carcinomas. (AFCR Annual Meeting; Biomedicine ’96, Washington, D.C., 1996.)

135.  Bentz, B.G., Haines, G.K., vonSchlegell A.S., Elseth, K.M., Hanson, D.G., and J.A.

Radosevich. Labyrinthin expression in salivary gland neoplasia. (Annual Meeting of the

American Academy of Otolaryngology – Head and Neck Surgery Foundation,

Washington, D.C., 1996.)

136.   Bellafiore, L., Sanderson, K., and J.A. Radosevich. Study on the Factors Affecting the

Accuracy and Reproducibility of Gradient Formation for Preparative LC. (Prep ‘98,

Washington, DC, 1998.)

137.   Diehl, E.E., Radosevich, J.A., Haines III, G.K., Yokoo, H., and L.A. Potempa. Studies

of the Anti-Tumor Activity of a Modified Form of C-Reactive Protein. (XVII

International Cancer Congress, Rio De Janeiro, Brazil, 1998.)

138.  Bentz, B.G., Haines III, G.K., Hanson, D.G., and J.A. Radosevich. Nitrotyosine

Implicates Nitric Oxide In Head and Neck Squamous Cell Carcinoma. (XVII

International Cancer Congress, Rio De Janeiro, Brazil, 1998.)

139.  Radosevich, J.A., Elseth, K.M., and G.K. Haines III. Pre-clinical Developments in the

Design of an Anti-Adenocarcinoma Vaccine For Humans Based On the Expresion of

Labyrinthin. (Presented at the XVII International Cancer Congress, Rio De Janeiro,

Brazil, 1998.)

140.  Bentz, B.G., Haines III, G.K., Hanson, D.G., and J.A. Radosevich. Nitrotyrosine as a

Marker of the Pathophysiologic Function of Nitric Oxide in Head and Neck Squamous

Cell Carcinoma. (American Society For Head and Neck Surgery/COSM, Palm Beach,

Florida, 1998.)

141.   Bentz, B.G., Haines III, G.K., Diehl, E.E., and J.A. Radosevich. Nitric Oxide In Head

and Neck Squamous Cell Carcinoma. (Midwest AFMR, Chicago, Illinois, 1998).

142.   Diehl, E.E., Radosevich, J.A., Haines III, G.K., Yokoo, H., and L.A. Potempa. Effects

of the Modified Form of C-Reactive Protein On Human Tumor Cells. (Midwest AFMR,

Chicago, Illinois, 1998).

1. Bentz, B.G., Haines III, G.K., and J.A. Radosevich. Endothelial Constitutuive Nitric

Oxide Synthase and Nitrotyrosine Co-localize in Squamous Cell Carcinoma of the Head

and Neck. (Triological Society Combined Otolaryngogology Spring Meeting Program,

Palm Springs, CA, 1999.)

1. Bentz, B.G., Haines III, G.K., and J.A. Radosevich. Glutathione-S-Transferase pi

expression Parallells Nitric Oxide In Head & Neck Squamous Cell Carcinoma.

(Triological Society Combined Otolaryngogology Spring Meeting Program, Palm

Springs, CA, 1999.)

1. Bentz, B.G., Haines III, G.K., Robinson, A.M., Shah, P, and J.A. Radosevich. Nitric

Oxide and Apoptosis in Head and Neck Squamous Cell Carcinomas. (5^th International

Conference On Head and Neck Cancer, San Francisco, 2000.)

1. Bentz, B.G., Haines III, G.K., and J.A. Radosevich. Glutathione S-Transferase Pi

Expression Parallels Nitric Oxide in Head and Neck Squamous Cell Carcinoma.

(Midwestern Sectional Meeting of the Triological Society, Cincinnati, OH, 2000.)

1. Chandra, R.K., Haines III, G.K., Bentz, B.G., Shah, P., and J.A. Radosevich. Expression

of NOS 3 in Reflux-Induced Esophageal Lesions. (Oto. Head Neck Surg. 123:P103, 2000.)

1. Chandra, R.K., Bentz, B.G., Haines III, G.K., Shah, P., Robinson, A.M., and J.A.

Radosevich. Expression of Nitric Oxide Synthase Type 3 in Gastric Mucosa, Metaplasia,

and Adenocarcinoma. (Midwestern Region ASCR, Chicago, IL, 2001.)

1. Bentz, B.G., Chandra, R., Haines III, G.K., Robinson, A. M., and J.A. Radosevich.

Endogenous or Exogenous Nitric Oxide Exposure Causes DNA Damage in Cancer. (AFCR:

Clinical Research 2001, Arlington, VA, 2001.)

1. Bentz, B.G., Chandra, R., Haines III, G.K., Robinson, A.M., and J.A. Radosevich. The role

Of Nitric Oxide in the Mutational Events Leading to Cancer Development. (Am. Soc. Clin.

Onc. Annual Meeting, San Francisco, CA, 2001.)

1. Lee, S., Hoffman, B.M., Barrett, A.G.M., Haines III, G.K., and J.A. Radosevich. Uptake

of Near-IR Absorbing/Emitting Porphyrazine (Tetraazaporphyrin) Macrocycles by Normal

and Tumor Cell Lines. (Midwestern Section AFCR, Chicago, IL, 2002.)

1. Chandra, R.K., Bentz, B.G., Wiet, R.J., Haines III, G.K., and J.A. Radosevich. Cyclin A

Expression in Acoustic Neuromas. (American Academy of Otolaryngology-Head and

Neck Surgery, San Diego, CA, 2002.)

1. Keni, S.P., Vakkalanka, S.K., Haines III, G.K., Radosevich, J.A., and K.W. Altman. Nitric

Oxide Synthase Type 3 Expression is Increased in Dysplastic Laryngeal Squamous

Papillomas. (The Annual Conference of the American Academy of Otolaryngology – Head

& Neck Surgery, San Diego, CA, 2002.)

1. Altman, K.W., Vakkalanka, S.K., Keni, S.J., Haines III, G.K., and J.A. Radosevich.

Thyroid Hormone Receptor Expression in the Mouse Larynx. (The Annual Conference

of the American Academy of Otolaryngology – Head & Neck Surgery, San Diego, CA, 2002.)

1. Bentz, B.G., Chandra, R., Haines III, G.K., and J.A. Radosevich. Endogenous or Exogenous

Nitric Oxide Exposure Causes DNA Damage in Cancer. (The Sixth Research Workshop on

the Biology, Prevention and Treatment of Head and Neck Cancer, Pittsburgh, PA, 2002.)

1. Radosevich, J.A., Bentz, B., and G.K. Haines III. Labyrithin is a Mutated Form of

Junctin/Junctate Associated With the Human Adenocarcinoma Phenotype. (Presented at: The

XXXth meeting of the International Society For Oncodevelopmental Biology and Medicine,

Boston, MA, 2002.)

1. Hammer, N.D., Lee, S., Hoffman, B.M., and J.A. Radosevich. Structural Correlation of the

Porphyrazines to Biological Activity. (American Federation for Medical Research, Chicago, IL, 2004.)

1. Hammer, N.D., Haines III, G. K., Altman, K., Bentz, B.G., Elseth, K., and J.A.Radosevich.

Transcriptional Analysis of the Human Aspartyl (asparaginyl) Beta-Hydroxylase Loci in Tumor

Cells and Identification of Labyrinthin, a Tumor Specific Transcript. (ISOBM 2004, Helsinki,

Finland, 2004).

159     Hammer, N.D., Vesper, B.J., Lee, S., Zong, H , Hoffman, B. M.,and J.A. Radosevich.

Structure-Function Correlations of Porphyrazines With Cell Killing. (ISOBM 2004,

Helsinki, Finland, 2004).

160     Radosevich, J.A., Hammer, N.D., Elseth, K., Hewitt, S. M., Babich, M., Bentz,

B.G, and G.K. Haines III. Expression of Calcium Ion Channel Components In

Human Tumors. (Presented at ISOBM 2004, Helsinki, Finland, 2004).

161.   Babich, M., Radosevich, J.A., Hammer, N.D., Elseth, K., Hewitt, S.M., Bentz B.G., and GK Haines III.

Selective Over Expression of Calcium Ion Channel Proteins In Human Tumors. (10^th Annual Cancer

Research Symposium, UC Davis Cancer Center, Sacramento, CA, 2005).

162.   Altman, K.W., Waltonen, J., Haines III G.K., Hammer ND, and J.A. Radosevich. Proton Pump Expression

in Human Laryngeal Seromucinous Glands. (Middle Section of the Triological Society, Chicago, IL,

2005).

163.   Vesper B., Hammer N., Elseth K., Lee S., Barrett A., Hoffman B., and J.A. Radosevich. Porphyrazine

Structure-Function Relationships: Effect of Peripheral Acid Groups on Cellular Toxicity. (2005 Clinic and

Research Day, Chicago, IL, 2005).

164.   Vesper B., Hammer N, Elseth K., Lee S., Barrett A., Hoffman B., and J.A. Radosevich. Changes in

Peripheral Methoxy Groups On Porphyrazines Affect Their Cellular Toxicity. (2005 Clinic and

Research Day, Chicago, IL, 2005).

165.   Tarjan S., Hammer N., Vesper B., Elseth K., Hewitt S., Babich M., Bentz B., Haines III G.K., and J.A.

Radosevich. Overexpression of Calcium Ion Channel Components in Human Tumors. (2005 Clinic and

Research Day, Chicago, IL, 2005).

166.  Elseth K., Hammer N., Vesper B., Bentz B., Haines III G.K., Roeske J., Mundt A., and J.A. Radosevich.

Nitric Oxide Synthatase and GST-pi Expression Correlates with Radiosensitivity in Human Oral Cancers.

(2005 Clinic and Research Day, Chicago, IL, 2005).

167.  Waltonen J., Altman K., Haines III G.K., Bentz B., Hammer N., Tarjan S., Elseth S., and J.A. Radosevich.

Over Expression of Glutathione-S-Transferase-pi (GST-pi) Does Not Parallel Over Expression of

Endothelial Constitutive Nitric Oxide Synthase (ecNOS) in Human Squamous Cell Laryngeal Tumors.

(2005 Clinic and Research Day, Chicago, IL, 2005).

168.  Waltonen J., Haines III G.K., Radosevich, J. A., Bentz B., and K.W. Altman. Evidence of Oxidative Injury

In The Human Laryngeal Squamous Papillomas. (Annual Meeting of the American Academy of

Otolaryngology – Head and Neck Surgery, Los Angeles, CA, 2005.)

169.  Waltonen J., Haines III G.K., Radosevich, J. A., Bentz B., and K.W. Altman.  Glutathione-S-Transferase

(GST-pi) is Over –Expressed in Radiation-resistant Human Squamous Cell Laryngeal Tumors. (American

Head and Neck Meeting, Boca Raton, FL 2005).

170.  Vesper, B. J., Hammer, N.D., Bentz, B.G., Haines, G.K., and J.A. Radosevich. Predicting Radiosensitivity:

Correlation of Nitric Oxide Synthatase and GST-pi Expression in Human Oral Cancers. (ISOBM 2005,

Rhodes, Greece 2005).

171.  Radosevich, J.A., Waltonen, J.D., Altman, K.W., Bentz, B.G., and G.K. Haines. Glutathione-S-Transferase-

pi (GST-pi) is Over-Expressed in Radiation-Resistant Human Squamous Cell Laryngeal Tumors. (Presented

at the ISOBM, 20005, Rhodes, Greece. 2005)

172.   Vesper, B.J., Hammer, N.D., Lee, S., Elseth, K., Hoffman, B.M., and J.A. Radosevich. Porphyrazine

Structure-Function Relationships: Effects of Core Metal and Number of Peripheral Acid Groups on

Biological Behavior. (ISOBM 2005, Rhodes, Greece 2005).

173.  Vesper, B.J., Hammer, N.D., Lee, S., Elseth, K., Hoffman, B.M., and J.A. Radosevich.  Charge

Dependence of Cellular Uptake and Selective Anti-Tumor Activity of Porphyrazines. (ISOBM 2005,

Rhodes, Greece 2005).

174.  Altman, M., Chura, S., Smith, B., Vesper, B., Radosevich, J., and J. Roeske. A Noval Phantom For Use In

3- Dimensional In Vitro Cell Experiments. (American Association of Physicists in Medicine 48^th Annual

Meeting, Orlando, FL, 2006).

175.  J.A. Radosevich. Three Examples of Translational Research At UIC College of Dentistry. (Clinic &

Research Day, Chicago, IL 2006).

176.  Mariscal, J.M., Vesper, B.J., and J.A. Radosevich. Spectral Imaging of Tissue Using Fiber Optics. (Clinic

&   Research Day, Chicago, IL 2006).

177.  Vesper, B.J., Zong, H., Hammer, N.D., Elseth, K., Barrett, A.G.M., Hoffman, B.M., and J.A. Radosevich.

Targeting Tumor Cell Receptors for Cancer Treatment: Estrogen-Functionalized Porphyrazines. (Clinic &

Research Day, Chicago, IL 2006).

178.  Elseth, K., Bentz, B.G., Haines III, G.K., Altmen, K.W., and J.A. Radosevich. Nitric Oxide Can Inhibit

Apoptosis in the Face of Ongoing Mutational Events by Altering Apoptosis-Related Gene Expression.

(Clinic &R esearch Day, Chicago, IL 2006).

179.  Khurram, H., Vesper, B.J., Elseth, K., Bentz, B.G., Haines, G.K., Gill, P., Tarjan, G., and J. A. Radosevich.

Expression of Inducible Nitric Oxide Synthase (iNOS) in Human Cervical Cancer. (Clinic & Research Day,

Chicago, IL 2006).

180.  Khurram, H., Gill, P., Elseth, K., Tarjan, G., Bentz, B., Altman, K., Haines III, G.K., and J.A. Radosevich.

Endothelial Constitutive Nitric Oxide Synthatase (ecNOS) and Inducible Nitric Oxide Synthatase (iNOS)

Are Inversely Over Expressed in Tumors of the Tongue. (Clinic & Research Day, Chicago, IL 2006).

181.  Elseth, K., Bentz. B.G., Vesper, B.J., Haines III, G.K., Altman, K.W., and J.A. Radosevich. Long-Term

Nitric Oxide Treated Human Tumor and Normal Cell Lines. (Clinic & Research Day, Chicago, IL 2006).

182. Vesper, B.J., Hammer, N.D., Elseth, K., Lee, S., Barrett, A.G.M., Hoffman, B.M., and J.A. Radosevich.

Preparation and Study of Acid-Functionalized Porphyrazines in the Treatment of Head and Neck Cancers.

(Clinic & Research Day, Chicago, IL 2006).

183.  Chhaya, V., Hammer, N.D., Pavlova, S., Elseth, K., Vesper, B.J., Altman, K.W., Tao, L., and J.A.

Radosevich. Drug Toxicity and Adverse Side Effects of Proton Pump Inhibitors: Effect of PPI on

Gastrointestinal Flora. (Clinic & Research Day, Chicago, IL 2006).

184.  Radosevich, J.A. and M. Babich. From The Gene Discovery of Labyrinthin To The Translational

Application of An Adenocarcinoma Vaccine. (Presented at the 2006 International Conference: Frontiers of

Pharmacology and Toxicology, Chicago, IL 2006).

185.  Altman, K.W., Waltonen, J.D., Tarjan, G., Radosevich, J.A., and G.K. Haines.  Human Lung Mucus Glands

Manifest Evidence Of The H+/K+-ATPase Proton Pump. (86^th Annual Meeting of The American

BronchoEsophagological Association, Chicago, IL. 2006).

186.   Gill, P.S., Khurram, H., Tarjan, G., Haines, G.K., and J.A. Radosevich. Overexpression of Nitric Oxide.

Synthase Isoforms (ecNOS and iNOS) In Squamous Cell Carcinoma of the Tongue. (2006 USCAP Annual

Meeting, Atlanta, GA, 2006).

187.   Chhaya, V., Hammer, N., Pavlova, S. Elseth, K., Vesper, B.J., Altman, K.W., Tao, L., and J.A.

Radosevich. Drug Toxicity and Adverse Side Effects in Gastroesophageal Reflux Disease (GERD): Effect

of Proton Pump Inhibitors (PPIs) on Gatrointestinal Flora. (Chicago Area Undergraduate Research

Symposium, Chicago, IL, 2006).

188.   Elseth, K., Bentz, B.G., Vesper, B.J., Yao, M., Haines, G.K., Altman, K., and J.A. Radosevich. Tumor

Cells Adapt More Quickly to Hight Levels of Nitric Oxide than Normal Cell Lines and Become More

Malignant in a High Nitric Oxide Environment. (American Head & Neck Society Annual Meeting,

Chicago, IL, 2006).

189.   Khurram, H., Vepser, B.J., Elseth, K., Targan, G., Bentz, B., Altman, K., Haines, G.K., and J.A.

Radosevich. Nitric Oxide Synthase Expression in Squamous Cell Carcinoma of the Tongue. (Sigma Xi

Science Graduate Research Forum, Chicago, IL, 2006).

190.   Vesper, B., Hammer, N.D., Lee, S., Elseth, K., Barrett, A.G.M., Hoffman, B.M., and J.A. Radosevich.

Acid-Functionalized Porphyrines Exhibit Anti-Tumor Behavior in Head and Neck Squamous Cell

Carcinomas. (The 4^th Chinese Conference of Oncology, Tainjin, China, 2006).

191.   Radosevich, J.A., Vesper, B.J., Elseth, K., Bentz, B.G., Altman, K.W., and G.K. Haines. Nitric Oxide

Inhibits Apoptosis-Related Gene Expression Via S-Nitrosylation In a Caspase-9 Dependent Fashion.

(Presented at The 4^th Chinese Conference of Oncology, Tainjin, China, 2006).

192.   Altman, K., Vesper, B., Tao, L., Hammer, N., Chhaya, V., and J.A. Radosevich. Proton Pump Expression

by Oral Cavity Bacteria. (110^th Annual meeting of the Triological Society, San Diego, CA, 2007).

193.  Khurram, H., Vepser, B.J., Elseth, K., Targan, G., Bentz, B., Altman, K., Haines, G.K., and J.A.

Radosevich. Over-Expression of Inducible Nitric Oxide Synthathase (iNOS) in Human Cervical

Carcinoma. (96th Annual Meeting United States and Canadian Academy of Pathology, San Diego, 2007.)

194.  Yarmolyuk, Y.R., Elseth, K., Vesper, B.J., Haines, G.K., Bentz, B.G., and J.A. Radosevich. Understanding

the Effects of Nitric Oxide on Tumor Formation and Progression. (Clinic & Research Day 2007, Chicago,

IL 2007.)

195.  Vesper, B.J., Lee, S., Zong, H., Hammer, N.D., Elseth, K., Barrett, A.G.M., Hoffman, B.M., and J.A.

Radosevich. The Isoindolines Are a New Class of Imaging and Therapeutic Agents For the Detection and

Treatment of Cancer. (Clinic & Research Day 2007, Chicago, IL 2007.)

196.  Vesper, B.J., Altman, M.B., Elseth, K., Roeske, J., and J.A. Radosevich. Development of a Novel

Intensity-Modulated Radiation Therapy (IMRT) Phantom to Mimic Patient Exposure During Radiation

Treatment. (Clinic & Research Day 2007, Chicago, IL 2007.)

197.  Elseth, K., Vesper, B.J., Lee, S., Zong, H., Hammer, N.D., Barrett, A.G. M., Hoffman, B.M., and J.A.

Radosevich. Structure-Function Studies of Porphyrazine Anti-Tumor Agents: New Class of Compounds

Found to Exhibit Light-Enhanced Toxicity. (Clinic & Research Day 2007, Chicago, IL 2007.)

198.  Chhaya, V., Hammer, N.D., Pavlova, S., Elseth, K., Vesper, B.J., Altman, K.W., Tao, L., and J.A.

Radosevich. The Effects of Proton Pump Inhibitors On the Bacterial Flora of Gastroesophageal Reflux

Disease (GERD) Patients. (Presented at the 5^th Joint Meeting on Medical Chemistry, Portoroz, Slovenia,

2007.)

199.  Radosevich, J.A., Yarmolyuk, Y.R., Elseth, K.M., Vesper, B.J., Haines, III, G. K., and Bentz, B..

Understanding the Role Nitric Oxide Plays in Tumor Formation and Progression.  (Presented at the 14^th

European Cancer Conference, Barcelona, Spain, 2007)

201.  Vesper, B.J., Lee, S., Zong, H., Hammer, N.D., Elseth, K., Barrett, A.G.M., Hoffman, B.M., and J.A.

Radosevich. Tumor Uptake and Photo-Enhanced Toxicity of Thiotriethoxy (ethoxy) methyl-Functionalized

Porphyrazines. (14^th European Cancer Conference, Barcelona, Spain, 2007)

202.  Vesper, B.J., Altman, M.B., Elseth, K.M., Roeske, J.C., Haines III, G.K., Altman, K.W., Bentz, B.G., and

J.A. Radosevich. Can Nitric Oxide Be Used as a Predictor of Radiation Response? (1^st International

Conference on Nitric Oxide and Cancer, Paris France, 2007.)

203. Radosevich, J.A., Vesper, B.J., Elseth, K.M., Haines III, G.K., Altman, K.W., and B.G. Bentz. Comparing

the Ability of Normal and Tumor Cells to Adapt to High Levels of Nitric Oxide. (Presented at the 1^st

International Conference on Nitric Oxide and Cancer, Paris France, 2007.)

204. Elseth, K.M., Vesper, B.J., Schwartz, J.L., Bentz, B., Haines III, G.K., and J.A. Radosevich. The Ability of

Nitric Oxide to Induce Carcinogenesis in Normal Cells. (Clinic & Research Day 2008, Chicago, IL, 2008.)

205. Khurram, H., Elseth, K.M., Vesper, B.J., Targan, G., Bentz, B., Haines III, G.K., and J.A. Radosevich.

Over-Expression of Nitric Oxide Synthase (NOS), Glutathione S-Transferase (GST-pi), and

Apurinic/Apyrimidinic Endonuclease (APE-1) in Tumors of the Tongue. (Clinic & Research Day 2008,

Chicago, IL, 2008.)

206.  Vesper, B.J., Altman, M.B., Elseth, K.M., Roeske, J.C., and J.A. Radosevich. Predicting Patient Response to

Radiation: In Vitro Cell Culture Studies Using an Intensity-Modulated Therapy (IMRT) Head & Neck

Phantom. (Clinic & Research Day 2008, Chicago, IL, 2008.)

207.  MacDonald, C.C., Elseth, K.M., Vesper, B.J., Bentz, B.G., Haines III, G.K., Altman, K.W., Tarjan, G. and

J.A. Radosevich. Apurinic/Apyrimidinic Endonuclease (APE-1) and Nitric Oxide Synthase Are Up-regulated

in Human Laryngeal Cancer. (Clinic & Research Day 2008, Chicago, IL, 2008.)

208.  Defranco, C., Schwartz, J., Alayyoubi, M., Zhou, C., Radosevich, J.A., and P. Gettins. Maspin: A new

Tumor Suppressor Protein for Oral Carcinogenesis and Tumorigenesis. (Clinic & Research Day 2008,

Chicago, IL, 2008.)

1. Radosevich, J.A., Yarmolyuk, Y.R., Vesper, B.J., Khurram, H., Tarjan, G., and G.K. Haines III. Development of a Human Tumor Tissue Culture System that Mimics Nitric Oxide Synthase Expression of Tumors Arising in the Tongue. (Presented at the 36^th ISOBM annual meeting, Tokyo, Japan, 2008).

210.  Radosevich, J.A., Vesper, B., Waltonen, J., Elseth, K., Tarjan, G., Altman, K., Bentz, B., and G. K. Haines.

Understanding the Role of Nitric Oxide and Related Gene Products in Human Tumors: An In Vitro Model

the Mimics Clinical Observations.  (2^nd International Workshop- Training Course On Molecular Medicine

and Drug Research, Karachi, Pakistan, 2009.)

211.  Elseth, K., Vesper, B.J., Haines III, G.K., Tarjan, G., and J.A. Radosevich. Aggressive Growth Behavior of

Human Oral Squamous Cell Lines Adapted to Nitric Oxide-Enriched Environments. (Clinic & Research

Day 2009, Chicago, IL, 2009.)

212.  Aparajita, R., Elseth, K., Vesper, B.J., Haines III, G.K., Tarjan, G., Kolokythas, A., J.A. Radosevich.

Expression of Argininosuccinate Synthetase (ASS) and Argininosuccinate (ASL) in Human Oral Squamous

Cell Carcinoma. (Clinic & Research Day 2009, Chicago, IL, 2009.)

213.  Vesper, B.J., Altman, M.B., Elseth, K.M., Haines III, G.K., Tarjan, G., Roeske, J.C., Bulent, A., and J.A.

Radosevich. Ultraviolet (UV) and X-ray Radiation Resistance of Oral Squamous Carcinoma Cell Lines

Adapted to Long-Term Nitric Oxide (NO) Exposure. (Clinic & Research Day 2009, Chicago, IL, 2009.)

214.  Vesper, B.J., Trivedi, E.R., Zong, H., Lee, S., Hoffman, B.M., and J.A. Radosevich. A New Subclass of

Porphyrazines Anti-Tumor Agents: Structure-Function Studies of Oxygen-Appended Porphyazines. (Clinic

& Research Day 2009, Chicago, IL, 2009.)

215.  Sroussi, H. Y., Lu, Y., Villines, D., Radosevich, J.A., and P.T. Marucha.  S100A8 and S100A8 Inhibit

Peripheral Neutrophil Oxidative Metabolism in a PKC Theta Dependent Pathway. (Clinic & Research Day

2009, Chicago, IL, 2009.)

216.  Aparajita, R., Elseth, K., Vesper, B.J., Haines III, G.K., Tarjan, G., Kolokythas, A., J.A. Radosevich.

Human Oral Tumors and Expression of Argininosuccinate Synthetase (ASS) and Argininosuccinate Lyase

(ASL).  (International Academy of Oral Oncology, Toronto, Canada, 2009).

217.  Yarmolyuk, Y.R., Elseth, K., Vesper, B.J., Haines III, G.K., Tarjan, G., and J.A. Radosevich. Aggressive

Behavior of Tumors Adapted to High Nitric Oxide Environments. (2009 Midwestern Regional Dental

Student Research Conference, Chicago, IL, 2009.)

218.  Yarmolyuk, Y.R., Elseth, K., Vesper, B.J., Haines III, G.K., Tarjan, G., and J.A. Radosevich. Adaptation of

Head and Neck Squamous Carcinoma Cells to a Nitric Oxide Environment Leads to More Aggressive

Growth. (2009 UIC Student Research Forum, Chicago, IL, 2009.)

219.  Radosevich, J.A., Tarjan, G., Elseth, K.M., Paradise, W.A., Vesper, B.J., Goel, A., and G.K. Haines III.

Development of a Novel Model System to Discover New Biomarkers Based On Nitric Oxide Induced Gene

Expression. (Presented at the 37^th Annual ISOBM Meeting, Amsterdam, Netherlands, 2009)

220.  Onul, A. Elseth, K., Verpser, B.J., Haines III, G.K., Tarjan, G., Goel, A., and J.A. Radosevich.  Effects of

Different Free Radical Donores on a Human Lung Cell Line Adapted to High Nitric Oxide (HNO) Levels.

(Clinic & Research Day 2019, Chicago, IL, 2010.)

221. Elseth, K., Onul, A., Vesper B.J., Haines, G.K., Tarjan, G., Goel, A., and J.A. Radosevich. Temperature

Resistance in High Nitric Oxide-Adapted Lung Adenocarcinoma Cells. (Clinic & Research Day 2019,

Chicago, IL, 2010.)

222. Malik, G., Elseth, K., Vesper, B.J., Haines III, G.K., Tarjan, G., Goel, A., and James A. Radosevich. Elevated

Expression of HIF-1 (alpha) in High Nitric Oxide-Adapted Human Lung Tumor Cells. (Clinic & Research Day

2019, Chicago, IL, 2010.)

223.  Vesper, B.E., Song, Y., Zong, H., Trivedi, E.R., Waters, A., Barrett, A.G.M., Hoffman, B.M., Meade, T.J., and

James A. Radosevich. Preparation and Characterization of Porphyrazine-Based Magnetic Resonance Imaging

Contrast Agents. (Clinic & Research Day 2019, Chicago, IL, 2010.)

224.  Paradise, W.A., Vesper, B.J., Altman, M.B., Elseth, K.M., Haines III, G.K., Tarjan, G., Roeske, J.C.,

Aydogan, B., and J. A. Radosevich. Gamma Radiation and Ultraviolet Resistance of a Breast Cancer Cell Line

Adapted to Long-Term Nitric Oxide Exposure. (Clinic & Research Day 2010, Chicago, IL, 2010.)

225.  Rubinstein, P., Lindgren, V., Setty, S., Yao, M., Pytynia, K.B., Radosevich, J.A., Kadkol, S.S., and L.E.

Feldman. Durable Complete Remission Induced by Cetuximab Monotherapy in an HIV Infected Patient With

Recurrent Squamous Cell Carcinoma of the Head and Neck. (ASCO, Chicago, IL, 2010.)

226.  Radosevich, J.A., Vesper, B.J., Paradise, W.A., Elseth, K.M., Xue, J., Haines III. G.K., Tarjan, G., and A.

Goel. A Human Lung Tumor Cell Line Exposed to Long-Term High Nitric Oxide Levels Exhibits Tumor

Stem Cell-Like Properties.  (Presented at the 11^th International Lung Cancer congress, Los Angeles, USA,

2010).

227.  Radosevich, J.A., Vesper, B.J., Paradise, B., Elseth, K., Xue, J., Targan, G., and G.K. Haines III Development

of a Human Tumor Tissue Culture System That Mimics Nitric Oxide Synthase Expression in Human Tumors.

(Presented at BIT3rd Annual World Cancer Congress -2010, Singapore, 2010).

228.  Radosevich, J.A., Vesper, B.J., Onul, A., Paradise, W.A., Elseth, K.M., Xue, J., Haines III, G.K., Tarjan, G.,

and A. Goel. The Role of Nitric Oxide in Human Lung Cancer: A Model System Based on a Cell Line

Exposed to Long-term Nitric Oxide. (Presented at 38^th ISOBM, Munich, Germany, 2010).

229.  Vesper, B.J., Tarjan, G., Haines III, G.K., Xue, J., Elseth, K. M., Paradise, W.A., Aydogan, B., and J.A.

Radosevich.  Understanding How Nitric Oxide Levels in the Cellular Microenvironment Affect Tumor

Aggressiveness in Squamous Cell Carcinomas. (9^th International Congress on Targeted Therapies in Cancer,

Washington, D.C., 2010)

230.   Kavak, G, Yeginer, M., Radosevich, J.A. and B. Aydrogan.  How many Arc is Enough? A Dosimetric

Comparison of RapidArc VMAT and Fixed Gantry IMRT for High-Risk Prostate Cancer. (Clinic & Research

Day 2011, Chicago, IL, 2011.).

231.   Ivanova, S.A., Onul, A., Elseth, K., Amegashie, C.P., Vesper, B.J., Gouvas, E., Haines III, G.K., Tarjan, G.,

Goel, A., and J. A. Radosevich.  Are High Nitric Oxide-Adapted Tumor ³Cells More Resistant to pH

Manipulation? (Clinic & Research Day 2011, Chicago, IL, 2011.).

232.    Elseth, K.M., Vesper, B.J., Gouvas, E., Onul, A., Xue, J., Paradise, W.A., Haines III, G.K., Tarjan, G., Goel,

A., and J. A. Radosevich.    Do Tumor Cells Adapted Long-Term to Nitric Oxide Exhibit Enhanced

Tumor Stem Cell-Like Properties? (Clinic & Research Day 2011, Chicago, IL, 2011.).

233.   Platt, F.J., Elseth, K.M., Onul, A., Vesper, B.J., Haines III, G.K., Aydogan, B., Tarjan, G., and J. A.

Radosevich. Elevated Hypoxia-Inducible Factor (HIF-1α) Expression in Human Tongue Carcinoma Cell

Lines Adapted to Long-Term Nitric Oxide Exposure. (Clinic & Research Day 2011, Chicago, IL, 2011.).

234.   Gouvas, E., Vesper, B.J., Tarjan, G., Haines III, G.K., Xue, J., Elseth, K.M., Paradise, W.A., Aydogan, B. and

J. A. Radosevich. Effects of High Nitric Oxide Levels on Tumor Behavior in Tongue Squamous Cell

Carcinomas. (Clinic & Research Day 2011, Chicago, IL, 2011.).

235.   Amegashie, C.P., Gouvas, E., Ivanova, S.A., Vesper, B.J., Elseth, K.M., Tarjan, G., Haines III, G.K., and

J. A. Radosevich. Effect of High Nitric Oxide Microenvironments on Oral Cancer Cell Migration.

(Clinic & Research Day 2011, Chicago, IL, 2011.).

236.   Glick, C.M., Vesper, B.J., Wilkie, J.R, Onul, A., Kavak, G.O., Aydogan, B., and J. A. Radosevich. Effect of

Daily Dose Variation in Radiation Treatment of Human Breast Tumors. (Clinic & Research Day 2011,

Chicago, IL, 2011.).

237.   Paradise, W.A., Onul, A., Gouvas, E., Vesper, B.J., Elseth, K.M., Xue, J., Garcia, K.D., Colvard, M.D. and

J. A. Radosevich. Comparative Evaluation of Staining Techniques for the Detection of Tissue Damage in

               Wounds. (Clinic & Research Day 2011, Chicago, IL, 2011.).

238.   Xue, J., Elseth, K.M., Onul, A., Vesper, B.J., Tarjan, G., Haines III, G.K., and J. A. Radosevich. Analysis of

High Nitric Oxide Tolerance in A549 Cells: A Biological Conundrum? (Clinic & Research Day 2011,

Chicago, IL, 2011.).

239.   Onul, A., Elseth, K. M., Vesper, B.J, Haines III, G.K., Tarjan, G., and J. A. Radosevich. Long-Term

Adaptation of a Human Lung Tumor to an Oxygen-Based Free Radical Donor. (Clinic & Research Day

2011, Chicago, IL, 2011.).

240.   Altman, K.W., Kinoshita, Y., Tan-Geller, M., Burstein, D., and J.A. Radosevich. Western Blot Confirmation

of the H+/K+-ATPase proton Pump in the Human Larynx and Submandibular Gland. (Annual Meeting of the

American Laryngological Association, Chicago, IL, 2011).

241.  Ivanova, S.A., Onul, A., Elseth, K.M., Vesper, B., and J.A. Radosevich. Are High Nitric Oxide Producing

Tumor Cells More Resistant to pH Change Than Low Producing Tumor Cells. (The Student Research Forum,

Chicago, IL, 2011.

242.  Radosevich, J.A., Onul, A., Gouvas, E., Elseth, K., Vesper, B.J., Paradise, W., Haines III, G.K., De Vetto, H.,

Rumjanek, F.D., and G. Tarjan. The Role of Nitric Oxide In Human Tumors – Changing The Way We Treat

Patients. (Presented at the 8^th International Scientific Conference, Astrakhan Medical Academy, Astrakhan,

Russia, 2011.)

243.  Aurisano, J., Radosevich, J.A., and J Leigh. Toward System-Level Visualizations of Molecular Networks on

Large-Scale, High Resolution. (BioVis 2011, Providence, RI, 2011).

244.   J.A. Radosevich. Improved Immunohistochemical Method For The Visualization Of Tissue Damage Caused

By Laser Exposure. (Presented at the 2011 AFMS Medical Research Symposium, National Harbor, M.D.,

2011.)

245.  De Vitto, H., Mendonca, B.S., Elseth, K.M., Onul, A., Noweder, A., Xue, J., Vesper, B.J., Gallo, C.V.M.,

Rumjanek, F.D., and J.A. Radosevich. Characterization of Human Breast Tumor Cell Lines BT-20 Adapted

to Long-Term High Nitric Oxide Exposure. (39^th ISOBM, Florence, Italy, 2011).

246.  De Vitto, H., Mendonca, B.S., Elseth, K.M., Onul, A., Vesper, B.J., Portari, E.A., Gallo, C.V.M.,

Radosevich, J.A., and F.D. Rumjanek. Assessment of Mitochondrial DNA Damage in Human Breast

Cancer. (39^th ISOBM, Florence, Italy, 2011).

247.   Gouvas, E., Amegashie, C., Elseth, K.M., Vesper, B.J., Haines III, G.K., Tarjan, G., and J.A. Radosevich.

Nitric Oxide Modulates HIF-1 alpha Expression in Human Lung Cancer. (39^th ISOBM, Florence, Italy,

2011).

248.   Radosevich, J.A., Elseth, K.M., and B.J. Vesper. The case for a New Tumor Stem Cell Theory: “Tumor Cell

Plasticity.” (Present at 39^th ISOBM, Florence, Italy, 2011).

249.   Onul, A., Elseth, K.M., Gouvas, E., Ivanova, S.A., Vesper, B.J., Aydogan, B., and J.A. Radosevich.

Expression of “Croass-Tolerance to a Wide Range of Conditions in a Human Lung Cancer Cell line After

Adaptation to Nitric Oxide. (39^th ISOBM, Florence, Italy, 2011).

250.   Onul, A., De Vitto, H., Elseth, K.M., Vesper, B.J., Deliu, Z., Rumjanek, F.D., and J.A. Radosevich.

Adaptation of a Human Lung Tumor to an Oxygen-Based Free Radical Donor. (39^th ISOBM, Florence,

Italy, 2010).

251.   Gouvas, E., Vesper, B.J., Tarjan, G., Haines III, G.K., Elseth, K.M., Aydogan, B., and J.A. Radosevich.

Daily Dose Variation of Radiation Effects on Human Breast Tumors.  (39^th ISOBM, Florence, Italy, 2011).

252.   Noweder, A., Platt, F., Onul, A., Bassiony, M., Vesper, B.J., Miresmaili, S., and J.A. Radosevich.

Cytotoxicity of Cinnamon Oil On Human Cancer Cells. (Clinic & Research Day 2011, Chicago, IL, 2012).

253.   Gouvas, E., Onul, A., Elseth, K.M., Deliu, Z., Ivanova, S.A., Noweder, A., Amegashie, C., Vesper, B.,

Paradise, W.A., Garcia, K.D., Colvard, M.D., and J.A. Radosevich. Laser Induced Tissue Damage From A

Newly Developed Hand-Held Thulium Laser. (Clinic & Research Day 2011, Chicago, IL, 2012).

254.   Sarigul, N., Radosevich, J., Koshy, M., Kavak, G., Ozturk, N., Smith, B., Yeginer, M., Awan, A., Surueu,

M., Patel, P., Rondelli, R., Welchselbaum, R., and B. Aydogen. (Clinic & Research Day 2011, Chicago, IL,

2012).

255.   Elseth, K., Vesper, B.J., Sweet, M., and J.A. Radosevich. Evidence Supporting a New Tumor Stem Cell

Theory. (Clinic & Research Day 2011, Chicago, IL, 2012).

256.    Huang, J., Kim, M., Elseth, K.M., Vesper, B.J., Bassiony, M., Aydrogan, B., And J.A. Radosevich.

Development of an Improved Soft Agar Method.  (Clinic & Research Day 2011, Chicago, IL, 2012).

257.   Paradise, W.A., Onul, A., Gouvas, E., Vesper, B.J., Elseth, K.M., Garcia, K.D., Colvard, M.D., and J.A.

Radosevich. Comparative Evaluation of Staining Techniques for the Detection of Tissue Damage Induced

by Directed Energy Devices (DEDs). (Clinic & Research Day 2011, Chicago, IL, 2012).

258.   Ivanova, S.A., Onul, A., Elseth, K.M., Vesper, B.J., Gouvas, E., Haines III, G.K., Tarjan, G., and J.A.

Radosevich. Human Breast Cancer Cells Adapted To An Oxygen Based Free Radical Environment Are

More Resistant To pH and Calcium Maniplulation. (Clinic & Research Day 2011, Chicago, IL, 2012).

259.  Deliu, Z., Onul, A., Elseth, K.M., Gouvas, E. Ivanova, S.I., Vesper, B.J., Noweder, A., Sweet, M.,

Aydogan, B., and J.A. Radosevich. Development of a Cell Line Model System Exhibiting

“Cross-Tolerance” to Diverse Environmental Stressors. (Clinic & Research Day 2011, Chicago, IL, 2012).

260.  Onul, A., Elseth, K., Vesper, B.J., Haines III, G.K., Paradise, W.A., Gouvas, E., Tarjan, G., and J.A.

Radosevich. Long-Term Adaptation of Human Tumor Cell Lines To An Oxygen-based Free Radical

Donor. (Clinic & Research Day 2011, Chicago, IL, 2012).

261.  Bassiony, M., Yang, J., Tawfeek, A-M., Elmogy, S. Elnagdy, M., and J.A. Radosevich. Ultrasonogaphy As

Diagnostic Tool In Staging of Maxillofacial Infections of Dental Origin. (Clinic & Research Day 2012,

Chicago, IL, 2012).

262.  Amegashi, C.P., Gouvas, E., Ivanova, S. A., Vesper, B.J., Elseth, K.M., Targan, G., Haines III, G.K., and

James A. Radosevich. Concentration Effect of Chemically Induced Hypoxia On The Metastasis of High

Nitric Oxide Adapted and Non-Adapted Cancer Cells. (Clinic & Research Day 2011, Chicago, IL, 2012).

263.  Elseth, K., Vesper, B.J., Sweet, M., and J.A. Radosevich. A New Tumor Stem Cell Theory – Data Toward

Validation. (UIC Cancer Center Research Forum 2011, Chicago, IL, 2012).

264.  Radosevich, J.A., Elseth, K., Vesper, B.J., Javadov, R., and M. Sweet. Evidence supporting A New Tumor

Stem Cell Plasticity Theory. (Presented at the 1^st Symposium on Head & Neck Cancer Stem Cells, Ann

Arbor, MI, 2012).

265.  Amegashie, C.P., Elseth, K.M., Vesper, B.J., Targan, G., Haines III, G.K., and J.A. Radosevich. The

Comparison of Motility in Parent Versus High Nitric Oxide Adapted Cells. (Illinois Mathematics and

Science Academy 2012, Aurora, IL, 2012).

266.  Radosevich, J.A., Elseth, K.M., Paradise, W.A., Deliu, Z., Desai, P.B., Thanki, D.H., Aqil, M., and M.

Bassiony. Nitric Oxide Exposure Results In Cross Tolerance. (Presented at the 40^th Annual ISOBM

Meeting, Jerusalem, Israel, 2012).

267.  Radosevich, J.A., Murphy, B. T., Wei, X., Elseth, K.M., Paradise, W.A., Aqil, M., and M. Bassiony. Tumor

Stem Cells: Do They Really Exist? (Presented at the 40^th Annual ISOBM Meeting, Jerusalem, Israel, 2012).

268.  Aqil, M., Elseth, K.M., Wei, X., Murphy, B.T., and J. A. Radosevich. Marine Microbial Secondary

Metabolites As Chemical Probes To Identify Novel Drug Targets In Lung Tumor Stem Cells. (26^th Annual

Clinic and Research Day 2013, Chicago, IL, 2013).

269.  Elseth, K.M., Vesper, B.J., Deliu, Z., Onul, A., Bassiony, M., Aqil, M., and J.A. Radosevich. Antioxidant

Effects of Equol and NaRLA on a Human Lung Cancer Cell Line Adapted to High Nitric Oxide. (26^th

Annual Clinic and Research Day 2013, Chicago, IL, 2013).

270.  Verma, R., Kim, K., Elseth, K.M., Aqil, M., De Vitto, H., and J. A. Radosevich. Hydrogen Peroxide

Production In High Nitric Oxide Adapted Human Lung Cancer Cells Which Express Tumor Stem Cell

“Like” Properties. (26^th Annual Clinic and Research Day 2013, Chicago, IL, 2013).

271.  Bassiony, M.A., Vesper, B.J., Colvard, M.D., Elseth, K.M., Garcia, K.D., Leigh, J., Mateevitsi, V.A., and

J.A. Radosevich.  A 3D Digital Evaluation of Lateral Tissue Damage of Incisional Wounds Treated With

The Biolase iLase Laser. (26^th Annual Clinic and Research Day 2013, Chicago, IL, 2013).

272.  Delui, Z., Elseth, K.M., Aqil, M., Onul, A., De Vitto, H., and J.A. Radosevich. High Hydrogen Peroxide

(HHP) Adapted Human Tumor Cells Are Prone To Grow Anaerobically. (26^th Annual Clinic and Research

Day 2013, Chicago, IL, 2013).

273.  Desai, P.B., Thanki, D.H., Elseth, K.M., Aqil, M., and J.A. Radosevich. Effect of High Nitric Oxide On

Lung Carcinoma Cell Adhesion. (26^th Annual Clinic and Research Day 2013, Chicago, IL, 2013).

274.  Kim, K., Verma, R., Elseth, K., Aqil, M., and J.A. Radosevich. Hydrogen Peroxide Production In High

Nitric Oxide Adapted Human Cancer Cells Which Express Tumor Stem Cell – Like Properties. (25^th

IMSALoquium, Aurora, IL, 2013).

275.  Budyn, E., Bhogle, S., Lacey, S., Radosevich, J.A., and M. Colvard. Thermal Identification During The

Cauterization Process In Porcine Skin. (USNCCM, Raleigh, N.C., 2013).

276.  Budyn, E., Bhogle, S., Lacey, S., Radosevich, J.A., and M. Colvard. Thermal Microenvironment of

Keratinocytes and Fibroblasts During Cauterization. (Bioengineering, Sunriver, OR., 2013).

277.  Radosevich, J.A., Elseth, K., Aqil, M., Dudek, A.Z., and L. Feldman. Supporting Evidence For A New

Tumor Stem Cell Plasticity Model Based On Adaptation To Nitric Oxide. (Presented at 15^th Annual

Meeting IASLC, Sydney, Australia, 2013).

278.   Dudek, A.Z., Aqil, M., Elseth, K.M., Feldman, L., Tarjan, G., and J.A. Radosevich. Nitric Oxide Adapted

Lung Tumor Cells Express Tumor Stem Cell-Like Markers. (15^th Annual Meeting IASLC, Sydney,

Australia, 2013).

279.  Vesper, B.J., Mateevitsi, V.A., Elseth, K.M., Bassiony, M.A., Colvard, M.D., Garcia, K.D., Leigh, J., and

J.A. Radosevich. Evaluation of Laser-Treated Tissue With A High Throughput 3-D Imaging Method.

(Presented at Pathology Visions 2012, San Antonio, TX, 2013).

280.  Budyn, E., Bhogle, S., Radosevich, J.A., and M.D. Colvard. Thermal Microenvironment of Keatinocytes

and Fifroblasts during Cauterixation by Laser Devices. (3^rd International Conference on Computational and

Mathematical Biomedical Engineering [CMBE 2013] Nithiaruasu P and R Lohner  [Eds.], Hong Kong,

2013).

281.  Elseth, K., Radosevich, J.A., Aqil, M., Dudek, A., and L. Feldman. Supporting evidence For A New Tumor

Stem Cell Plasticity Model Based on Adaptation to Nitric Oxide. (J. Thoracic Oncology, 8:S1042-S1042;

2013).

282.   Aqil, M., Elseth, K.M., Kolonda, J., and J.A. Radosevich. HNOS Adapted A549 Cells Show Reduced

Surface CEACAM Expression And Enhanced Migration. (27^th Annual Clinic and Research Day 2014,

Chicago, IL, 2014).

283.  Arjunakani, A., Nebres, P., Aqil, M., Elseth, K., and J.A. Radosevich. The Effect of Nitric Oxide On

Cellular Adhesion For Various Cancer Cell Lines. (27^th Annual Clinic and Research Day 2014, Chicago,

IL, 2014).

284.  Bassiony, M.A., Vesper, B.J., Mateevitisi, V.A., Elseth, K.M., Colvard, M.D., Garcia, K.D., Leigh, J., and

J.A. Radosevich. Immunohistochemical Evaluation of Bleeding Control Induced By Holmium Laser and

Biolase Dental Laser As Coagulating Devices of Incisional Wounds. (27^th Annual Clinic and Research Day

2014, Chicago, IL, 2014).

285.  Elseth, K., Amegashie, C., Aqil, M., Tarjan, G., and J.A. Radosevich. Adaptation To Nitric Oxide

Exposure Leads To Resistance to Hypoxia In A549 Lung Cancer Cells. (27^th Annual Clinic and Research

Day 2014, Chicago, IL, 2014).

286.  Kolonda, J., Elseth, K.M., Aqil, M., Amegashie, C.P., and J.A. Radosevich. Metastatic Properties Of High

Nitric Oxide Cells vs Parent Cells. (27^th Annual Clinic and Research Day 2014, Chicago, IL, 2014).

287.   Dixon- Rojas, M., Elseth, K., Aqil, M., Bassiony, M., Sayres, J., Vesper, B., and J.A. Radosevich.

Lipoclain 2 (LCN2) Is Consistently Up-Regulated In Head & Neck Cancer Cell lines Adapted To High

Nitric Oxide (HNO) Levels. (27^th Annual Clinic and Research Day 2014, Chicago, IL, 2014).

288.   Sayres, J., Aqil, M., Deliu, Z., Onul, A. Elseth, K.M., Aydogan, B., and J.A. Radosevich. Development of

A Human Lung Cancer Model System Exhibiting “Cross – Tolerance” to Diverse Environmental Factors.

(27^th Annual Clinic and Research Day 2014, Chicago, IL, 2014).

289.   Song, Q., Aqil, M., Elseth, K.M., and J.A. Radosevich. Role of CA2+ Regulatory Proteins STIM1 And

ORAI 1In A High Nitric Oxide Adapted Stem – Like Human Lung Adenocarcinoma Cells.  (27^th Annual

Clinic and Research Day 2014, Chicago, IL, 2014).

290.   Aqil, M., Elseth, K., Kolonda, J., and J.A. Radosevich. Reduced Surface CEACAM Expression and Enhanced Migration in A549 Nitric Oxide Adapted Lung Carcinoma Cells. (UIC-Cancer Research Forum 2014, Chicago, IL 2014).

291.    Bassiony, M., Sayres, J., Aqil, M., Elseth, K., Radosevich, J.A., and B. Aydogan. Long Term Development of a Human Lung Cancer Model System Exhibiting “Cross-Tolerance” to Diverse Environmental Stressors. (UIC-Cancer Research Forum 2014, Chicago, IL 2014).

292.   Song, Q., Aqil, M., Elseth, K.M., and J.A. Radosevich. Increased STIM1 and ORAI1 Expression May Contribute to the Apoptotic Resistance of the High Nitric Oxide (HNO) Adapted Human Lung Adenocarcino A549 Cells. (UIC-Cancer Research Forum 2014, Chicago, IL 2014).

293.   Elseth, K., Amegashie, C., Aqil, M., Tarjan, G., and J.A. Radosevich. Hypoxia-Induced Resistance to long Term Exposure of Nitric Oxide in A549 Lung Cancer Cells. (UIC-Cancer Research Forum 2014, Chicago, IL 2014).

294.   Radosevich, J.A., Kuganeswaran, R., Luna, C., Deliu, Z., Hamed, D., Aqil, M.m Al Oweidi, A., Khalili, M., M. Bassiony. The Role of Nitric Oxide in Human Tumor Stem Cell Development: A New Theory About Tumor Stem Cells and New Drugs to Kill Them. (National Conference on Pure and Applied Chemistry, Mysore, India, 2014).

295.   Deliu, Z., Dixon-Rojas, M., Elseth, K, Aqil, M., Bassiony, M., Vesper, B., and J.A. Radosevich. Head & Neck Cell Lines Adapted to High Nitric Oxide (HNO) Levels Consistently Up-Regulate Lipocalin 2 (LCN2). (9^th International Conference of Anticancer Research, Potro Carras, Sithonia, Greece, 2014).

296.   Radosevich, J.A., Murphy, Brian, T., Wei, X., Elsesth, K.M., Deliu, Z., Aqil, M., and M. Bassiony. A New Way to Think About Tumor Stem Cells.  (9^th International Conference of Anticancer Research, Potro Carras, Sithonia, Greece, 2014).

297.   Radosevich, J.A., Dixon-Rojas, M., Elseth, K., Aqil, M., Bassiony, M., and B. Vesper. Lipocalin 2 (LCN2) is Consistently Up-Regulated in Head and Neck High Nitric Oxide Adapter Cells Which Exhibit Tumor Stem Cell Properties. (41^st Congress ISOBM, Barcelona, 2014).

298.    Dixon – Rojas, M., Elseth, K., Aqil, M., Bassiony, M., Sayres, J., Vesper, B., J.A. Radosevich. Adaptation to High Nitric Oxide (HNO) in Head and Neck Cancer Cell Lines Consistently Up-Regulated Lipocalin 2 (LCN2) (UIC Cancer Forum, Chicago, 2014).

299     Luna, C., Zick, A., Alwidi, A., Hamed, D., Dixon – Rojas, M., Aqil, M., Bassiony, M., and J.A. Radosevich. Genomic Mutational Analysis of High Nirtic Oxide Adapted Human Lung Adenocarcinoma Cells Compared to Parent Cells. (28^th Annual Clinic and Research Day 2015, Chicago, IL, 2015).

300.    Al Oweidi, A., Kuganeswaran, R., Luna, C., Deliu, Z., Hamed, D., Aqil, M., Khalili, M., and J.A. Radosevich. Exposure to Nitric Oxide Causes Over- Expression of SOX2 and SOX21 Genes in A549 Lung Cancer Cells. (28^th Annual Clinic and Research Day 2015, Chicago, IL, 2015).

301.   Hamed, D. and J.A. Radosevich. The effects of Inducible and Endothelial Nitric Oxide on Cancerous Tumor Cells.  (28^th Annual Clinic and Research Day 2015, Chicago, IL, 2015).

302.   Radosevich, J.A., Kuganeswaran, R., Luna, C., Deliu, Z., Hamed, D., Aqil, M., Al Oweidi, Khalili, M., And M. Bassiony. Nitric Oxide in Human Tumor Stem Cell Development: Tumor cells Have the Plasticity to Become Tumor Stem Cells. (Presented at the Academic Conference Program to Celebrate 19^th Anniversary Faculty of Dentistry, Thammasat University, Bangkok, Thailand, 2015).

303.  Radosevich, J.A., Aqil, M., and M. Bassiony. Rethinking the Tumor Stem Cell Theory.  (Presented at the 42^nd annual ISOBM, Zakopane, Poland, 2015).

304.   Radosevich, J.A., Aqil, M., and M. Bassiony. A new way to look at Treating Cancer – The Cancer Cell Plasticity Model. (Presented at the 103^rd All India Science Conference, Mysore, India 2016).

305.   Rojas, M.D., Tamas, T. and J.A. Radosevich. NO Adapted Head & Neck Cancer Cells Have Up-regulated C-Jun.  Annual Meeting of the AADR/CADR, Los Angeles, CA, 2016).

306.  Tamas, T.J., Myat, A., and J.A. Radosevich. Head & Neck (H&N) Squamous Cell carcinomas (SCC) Adapted to High Nitric Oxide Over Express Transmembrane Glycoprotein NMB (GPNMB). (29^th Annual Clinic and Research Day 2015, Chicago, IL, 2016).

307.  Wan, T., Kuganeswaran, N., Korrapati, K., and J.A. Radosevich. Molecular Mechanisms of Adenocarcinoma (ACs) Tumor Stem Cell (TSC) Creation via High Nitric Oxide (HNO) Adaptation. (29^th Annual Clinic and Research Day 2015, Chicago, IL, 2016).

308.  Khurana, R., Tamas, T.J., Myat, A., Vahdatian, and J.A. Radosevich. Up-Regulation of Cell Division cycle Protein 27 (CDC27) is Observed in High Nitric Oxide-Adapted Breast Cancer Cell Lines. (29^th Annual Clinic and Research Day 2015, Chicago, IL, 2016).

309.  Kuganeswaran, N., Korrapati, K., Wan, T., and J.A. Radosevich.  Molecular Mechanisms of Squamous Cell Carcinoma Tumor Stem Cell Creation via High Nitric Oxide (HNO) Adaption. (29^th Annual Clinic and Research Day 2015, Chicago, IL, 2016).

310.  Myat, A., Tamas, T., Khurana, R., Vahdatian, M., and J.A. Radosevich. Head & Neck Squamous Cell Carcinomas (SCC) Adapted to High Nitric Oxide Show Down-Regulation of Caherin-1, Type 1. (29^th Annual Clinic and Research Day 2015, Chicago, IL, 2016).

311.  Korrapati, K., Kuganeswaran, N., Wan, T., Tamas, T.J., and J.A. Radosevich. Role of Pseudogenes in Cancer Stem Creation Via High Nitric Oxide Adaptation. (29^th Annual Clinic and Research Day 2015, Chicago, IL, 2016).

312.  Rojas, M.D., Tama, T., and J.A. Radosevich. No Adapted Head & Neck Cancer Cells Have Up-Regulated JUN, FOS, & AP1. (29^th Annual Clinic and Research Day 2015, Chicago, IL, 2016).

313.  Chowdhury, J., Batool, K., Tamas, T.J., Khurana, R., Vahdatian, M., Tamas, N., and J.A. Radosevich. The Cadherin-1, Type-1 (CDH1) Gene is Down Regulated by High Nitric Oxide Levels in Head & Neck Squamous Cell Carcinomas (SCC). (43^rd ISOBM Annual Congress, Chicago, IL 2016).

314.  Chowdhury, J., Deliu, Z., Batool, K., Yang, S., Tamas, T.J., Desai, P., Tamas, N., Vahdatian, M., and J.A. Radosevich. Cell Division Cycle Protein 27 (CDC27) Is Down-Regulated In High Nitric Oxide-Adapted Breast Cancer Cell Lines.  (43^rd ISOBM Annual Congress, Chicago, IL 2016).

315.  Bassiony, M., Chowdhury, J., Batool, H., Wan, T., Kuganeswaran, Korrapati, K., Tamas, T.J., and J.A. Radosevich. Tumor Stem Cell (TSC) Creation via High Nitric Oxide (HNO) Adaptation in Adenocarcinomas (Acs). (43^rd ISOBM Annual Congress, Chicago, IL 2016).

316.  Batool, K., Chowdhury, J., Korrapati, K., Kuganeswaran, N.T., Wan, T., Tamas, T.J., and J.A. Radosevich. Pseudogenes May Play a Role in Cancer Stem Cell Formation via Increased Nitric Oxide (NO) Exposure. (43^rd ISOBM Annual Congress, Chicago, IL 2016).

317.  Chowdhury, J., Yang, S., Batool, K., Desai, P., Thomas, J., Vahdatian, M., Korrapati, K., Kuganeswaran, N., Wan, T., Tamas, T., and J.A. Radosevich. High Nitric Oxide Adapted Tumor Cells Ensure Survival by Up or Down Regulating Specific Genes Within The Apoptosis Pathway. (43^rd ISOBM Annual Congress, Chicago, IL 2016).

318.  Deliu, Z., Batool, K., Chowdhury, J., Thomas, J., Desai, P., Vahdatian, M., Tamas, T.J., Myat, A., and J.A. Radosevich. Transmembrane Glycoprotein NMB (GPNMB) is Over-expressed in Head & Neck (H&N) Squamous Cell Carcinomas (SCC) Exposed To Increased Levels of Nitric Oxide (NO). (43^rd ISOBM Annual Congress, Chicago, IL 2016).

319.  Batool, H., Chowdhury, J., Batool, K., Thomas, J., Tamas, N., and J.A. Radosevich. JUN, FOS, & AP1 Are Upregulated in High Nitric Oxide (NO) Exposed Head & Neck Cancer Cells. (43^rd ISOBM Annual Congress, Chicago, IL 2016).

320.  Jurisic, V., Vukajlovic, M., Nedeljkov-Jancic,R., Markovic, S.D., and J.A. Radosevich. Reactive Oxygen Species in Non-Hodgkin’s Lymphoma Patients. (43^rd ISOBM Annual Congress, Chicago, IL 2016).

321.  Sharma, A., Radosevich, J.A., and C.C. Mandal. Cold Environment Is A Risk Factor For Cancer. (43^rd ISOBM Annual Congress, Chicago, IL 2016).

322.  Sharma, A., Radosevich, J.A., and C.C. Mandal. Omega-3 Fatty Acid Disrupts Osteoblastic Potential of Breast Cancer Cells. (43^rd ISOBM Annual Congress, Chicago, IL 2016).

323.  Vahdatian, M., Chowdhury, J., Batool, K., Thomas, J., Tamas, N., and J.A. Radosevich. Down Regulation Of Condensin Complex 1 Protein In Head & Neck (H&N) Squamous cell Cancer (SCC) Cell Lines Adapted To High Levels of Nitric Oxide (NO). (43^rd ISOBM Annual Congress, Chicago, IL 2016).

324.  Radosevich, J.A., Babich, M., and H. Slor. Development of the Adenocarcinoma Marker Labyrinthin as a Synthetic Peptide Vaccine. (Presented at the Global Conference and Expo on Vaccine Research, Kuala Lumpur, Malaysia 2016).

325.  Radosevich, J.A., Babich, M., and H. Slor. Development of a Synthetic Peptide Vaccine Based on the Tumor Marker Labyrinthin For Human Lung Adenocarcinomas. (Presented at the 2017 PCS International Pulmonary Forum, Marrakech, Morocco 2017).

326. Radosevich, J.A., Babich, M., and H. Slor. Development of a Synthetic Peptide Vaccine Based on the Adenocarcinoma Marker Labyrinthin. (Presented at the PCS 4^th Annual Global Cancer Conference. Lisbon, Portugal,2018).

327. Covington, J., Chowdhury, J., Batool, K., Bano, S., Baksh, M., and J.A. Radosevich. Small GTPase Genes Altered in Expression Linked to Change in A549 Phenotype Due to Increase NO Overexpression. (31^th Annual Clinic and Research Day, Chicago, IL, 2018).

328.  Chowdhury, J., Batool, K., Covington, J., Bano, S., Baksh, S., and J.A. Radosevich. Altered Genetic Expression of Adapted Lung Adenocarcinoma Cell Line towards Angiogenesis. (31^th Annual Clinic and Research Day, Chicago, IL, 2018).

329. Bano, S., Covington, J., Chowdhury, J., Batool, K., Baksh, M., and J.A. Radosevich. Nitric Oxide and its Effect on Cellular Nuclear Migration. (31^th Annual Clinic and Research Day, Chicago, IL, 2018).

330. Baksh, M., Covington, J., Batool, K., Chowdhury, J., Bano, S., and J.A. Radosevich. Comparison Analysis Between DNA Replication Genes With Altered Expression Due to High NO Adaptation in A549 Cancer Cells. (31^th Annual Clinic and Research Day, Chicago, IL, 2018).

331. Myat, A., Tamas, T.J., Covington, J., Khurana, Rohan, Vadatian, M., and J.A. Radosevich. Head & Neck Squamous Cell Carcinomas (SCC) Adapted to High Levels of Nitric Oxide Show Down-Regulation of Cadherin -1 Type-1 (CDH1). (UIC Student Forum 2018, Chicago, IL, 2018).

332. Covington, J., Chowdhury, J., Batool, K., and J.A. Radosevich. The Altered Expression of Small GTPase genes Coincided With Alterations of the Phenotype in A549 Cells due to an Increase of NO Exposure. (UIC Student Forum 2018, Chicago, IL, 2018).

333.  Kaur, H., Yahairi, Y. Cheruku, S., Betzelos, P., Covington, J., Al-Turkmani, A., Patel, H, Chowdhury, J., Batool, K., and J. A. Radosevich. Microsatellite Instability Pathway and Molecular Genetics of MLH1 Gene. (32^th Annual Clinic and Research Day, Chicago, IL, 2018).

334.  Mahairi, Y., Cheruku, S., Betzelos, P., Covington, J., Al-Turkmani, A., Patel, H., Kaur, H., Chowdhury, J., Batool, K., and J. A., Radosevich. Genes Related to UV-B Response are altered by NO Exposure. (32^th Annual Clinic and Research Day, Chicago, IL, 2018).

335.  Al-Turkmani, A., Cheruku, S., Betzelos, P., Covington, J., Mahairi, Y., Patel, H., Kaur, H., Chowdhury, J., Batool, K., and J. A. Radosevich. NO Exposure In Tumor Cells Changed Radiation Response Of Genes. (32^th Annual Clinic and Research Day, Chicago, IL, 2018).

336.  Cheruku, S., Betzelos, P., Covington, J., Al-Turkmani, A., Mahairi, Y., Patel, H., Kaur, H., Chowdhury, J., Batool, K., and J. A. Radosevich. Apoptotic Gene Response to Nitric Oxide Exposure in A549 Cells. (32^th Annual Clinic and Research Day, Chicago, IL, 2018).

337.  Betzelos, P., Cheruku, S., Covington, J., Al-Turkmani, A., Mahairi, Y., Patel, H., Kaur, H., Chowdhury, J., Batool, K., and J.A. Radosevich. Notch Signaling Pathway Is Altered In Aggressive A549-HNO Cells. (32^th Annual Clinic and Research Day, Chicago, IL, 2018).

338.  James Covington, Betzelos, P., Cheruku, S., Al-Turkmani, A., Mahairi, Y., Patel, H., Kaur, H., Chowdhury, J., Batool, K., and J.A. Radosevich.  L-glutamate Transport Altered in A549 Cells From High NO Exposure. (32^th Annual Clinic and Research Day, Chicago, IL, 2018).

339.  Cheruku, S., Kovlari, A., Al-Turkmani, A., Diab, M., Kaur, H., Haider, S., and J.A. Radosevich. DNA Damage Response To Nitric Oxide Exposure In A549 Cells. (33^th Annual Clinic and Research Day, Chicago, IL, 2019).

340.   Diab, M., Cheruku, S., Haider, S., Al-Turkmani, A., Kovlari, A., and J.A. Radosevich. Cellular Response To Exposure Of Elevated Levels of Nitric Oxide. (33^th Annual Clinic and Research Day, Chicago, IL, 2019).

341.   Kovlari, A., Al-Turkmani, A., Haider, S., Cheruku, S., Diab, M., and J.A. Radosevich. Effects of Hydrogen Peroxide in High Nitric Oxide Adapted Cells.  (33^th Annual Clinic and Research Day, Chicago, IL, 2019).

342.   Kaur, H., Cheruku, S., Kovlari, A., Al-Turkmani, A., Diab, M., and J.A. Radosevich. Molecular Fingerprint Of Deficient Mismatch Repair and Structure And Activity of MLH1 Gene. (33^th Annual Clinic and Research Day, Chicago, IL, 2019).

343.   Haider, S., Kaur, H., Diab, M., Kovlari, A., Al-Turkmani, A., Cheruku, S. and J.A. Radosevich. Altered Expression of ACC Genes In High NO Adapted Cells. (33^th Annual Clinic and Research Day, Chicago, IL, 2019).

344.   Al-Turkmani, A., Kovlari, A., Haider, S., Diab, M., Kaur, H., Cheruku, S., and J.A. Radosevich. High Nitric Oxide Adaptation Caused Altered Microtubule Gene Expression. (33^th Annual Clinic and Research Day, Chicago, IL, 2019).

• PhD, University of Illinois, Chicago, Illinois
• BS, Bradley University, Peoria, Illinois

Head & neck cancer
Lung & upper aerodigestive tumors
Labyrithin biology in human tumors
Lasers and PDT
Human tumor stem cells