Director, Laboratory of Applied Dental Biomaterials and Interfaces
Education & Career
- Aracatuba School of Dentistry, Brazil, DDS
- CranioFacial Anomalies Center in Bauru, Brazil, hospital residency
- Piracicaba School of Dentistry, Brazil, MS, 2000
- Piracicaba School of Dentistry, Brazil, PhD, 2003
- University of North Carolina at Chapel Hill, NC, post-doctoral work, 2004
- University of Illinois at Chicago, post-doctoral work, 2005
The tooth is a very complex structure that can be modified over time due to aging and disease process. It is important to understand the biochemical and mechanical properties of the tooth in order to develop reparative/regenerative biomaterials to replace lost tooth structure. Therefore, we conduct studies to investigate the mechanical and biochemical properties of specific sites in the tooth and also investigate the interface between biomaterials and the tooth structures. Using a biomimetic approach, we study the use of agents that can strengthen the tooth and consequently improve the properties of the tooth and tooth-restoration interface. In addition, our laboratory investigates the effects of various biomaterials applied to the tooth and their potential effect on the tooth properties.
Leme AA, Vidal CM, Hassan LS, Bedran-Russo AK. Potential role of surface wettability on the long-term stability of dentin bonds after surface
biomodification. J Biomech. 2015 Jul 16;48(10):2067-71.
Padovano JD, Ravindran S, Snee PT, Ramachandran A, Bedran-Russo AK, George A. DMP1-derived peptides promote remineralization of human dentin. J Dent Res. 2015 Apr;94(4):608-14.
Vidal CM, Leme AA, Aguiar TR, Phansalkar R, Nam JW, Bisson J, McAlpine JB, Chen SN, Pauli GF, Bedran-Russo A. Mimicking the hierarchical functions of dentin
collagen cross-links with plant derived phenols and phenolic acids. Langmuir. 2014 Dec 16;30(49):14887-93.
Vidal CM, Aguiar TR, Phansalkar R, McAlpine JB, Napolitano JG, Chen SN, Araújo LS, Pauli GF, Bedran-Russo A. Galloyl moieties enhance the dentin biomodification
potential of plant-derived catechins. Acta Biomater. 2014 Jul;10(7):3288-94.
Bedran-Russo AK, Pauli GF, Chen SN, McAlpine J, Castellan CS, Phansalkar RS, Aguiar TR, Vidal CM, Napotilano JG, Nam JW, Leme AA. Dentin biomodification:
strategies, renewable resources and clinical applications. Dent Mater. 2014 Jan;30(1):62-76.