Antonia Kolokythas, DDS, MS

Associate Professor
Director of Research
UICollaboratory Profile

Research Interests

Dr. Kolokythas is an Oral and Maxillofacial Surgeon with fellowship training in oral /head and neck oncology and reconstruction. Her clinical and research interests focus on oral cancer and specifically early detection that significantly impacts on survival. For the last 3 years under Dr. Adami's guidance and in collaboration with Dr. Schwartz, her research has focused on gene expression analysis in oral squamous cell carcinoma in high risk population using RNA from brush cytology. It is her main interest to improve detection of early cancers and high risk oral pre-malignant lesions and employ non-invasive methods to study gene expression changes associated with these lesions. This will allow for early detection and intervention and can be used for surveillance without need for invasive procedures. Her scope of practice is quite unique as it is almost exclusively dedicated to treatment of oral pathology and oral /head and neck cancer. She is part of the multidisciplinary head and neck cancer clinic (the first multidisciplinary cancer clinic established at the UIC Cancer Center) and she treats patients using state of the art techniques that include immediate reconstruction of post ablative defects using virtual planning and medical modeling with and without free flap transfer. She is co-investigator in several funded research projects at the UIC COD as well as several ongoing clinical trials at the Cancer Center. She has established and is maintaining the "UIC College of Dentistry Tissue Depository" which is the first ever established tissue bank with fresh frozen tissue samples available exclusively to the researchers at the COD. The tissue bank is a vital component for the support and advancement of the "Center of Molecular Biology and Oral Diseases" as well as all researchers at the COD that need immediate access to high quality tissue to advance their research projects.


Kolokythas A, Schwartz JL, Pytynia KB, Panda S, Yao M, Homann B, Sroussi HY, Epstein JB, Gordon SC, Adami GR. Analysis of RNA from brush cytology detects changes in B2M, CYP1B1 and KRT17 levels with OSCC in tobacco users. Oral Oncology. 2011 Jun;47(6):532-6. Epub 2011 May 5.

Schwartz J, Pavlova S, Kolokythas A, Lugakingira M, Tao L, Miloro M. Streptococci-Human Papilloma Virus Interaction With Ethanol Exposure Leads to Keratinocyte Damage. Journal of Oral Maxillofacial Surgery. 2011 Nov 10.


Kolokythas A, Karas M, Sarna T, Flick W, Miloro M. Does Cytokine Profiling of Aspirate From Jaw Cysts and Tumors Have a Role in Diagnosis? Journal of Oral Maxillofacial Surgery. 2011 Jul 28.

Kolokythas A, Schlieve T, Miloro M. Simple method for securing a decompression tube for odontogenic cysts and tumors: a technical note. Journal of Oral Maxillofacial Surgery. 2011 Sep;69(9):2392-5. Epub 2011 Jul 1

Kolokythas A, Al-Ghamian H, Miloro M. Does a difference exist in inferior alveolar canal displacement caused by commonly encountered pathologic entities? An observational study. Journal of Oral and Maxillofacial Surgery. 2011 Jul;69(7):1944-51. Epub 2011 Mar 21.


Dr. Kolokythas


Research Areas