- DDS, MS, PhD
- Director, Laboratory of Applied Dental Biomaterials and Interfaces
- Program Director, Multidisciplinary Oral Sciences Training Program
- Caries ResearchBiomaterialsBio-engineeringDental Implants
Dr. Bedran-Russo's research focuses on the mechanical and biochemical properties of teeth and the interface between biomaterials and tooth structure. Her research team also carries out experimental and clinical studies on the localized biological responses induced by preventive and reparative dental biomaterials. Dr. Bedran-Russo has published more than 65 scientific peer reviewed papers and over 100 abstracts. Her research is funded by the NIH.
Dr. Bedran-Russo was named a Rising Star in Clinical Sciences and received the 2014 UIC Researcher of the Year award. As the leader of the Multidisciplinary Oral Sciences Training Program (MOST) she is dedicated to train future clinician-scientists. Dr. Bedran-Russo is also the president of IADR Dental Materials group and has organized several national and international meetings including the 2016 Academy of Dental Materials meeting here in Chicago.
Education & Career
- Aracatuba School of Dentistry, Brazil, DDS, 1997
- CranioFacial Anomalies Center in Bauru, Brazil, hospital residency, 1998
- Piracicaba School of Dentistry, Brazil, MS, 2000
- Piracicaba School of Dentistry, Brazil, PhD, 2003
- University of North Carolina at Chapel Hill, NC, post-doctoral work, 2004
- University of Illinois at Chicago, post-doctoral work, 2005
The tooth is a very complex structure that can be modified over time due to aging and disease process. It is important to understand the biochemical and mechanical properties of the tooth in order to develop reparative/regenerative biomaterials to replace lost tooth structure. Therefore, we conduct studies to investigate the mechanical and biochemical properties of specific sites in the tooth and also investigate the interface between biomaterials and the tooth structures. Using a biomimetic approach, we study the use of agents that can strengthen the tooth and consequently improve the properties of the tooth and tooth-restoration interface. In addition, Dr. Bedran-Russo’s group carry out experimental and clinical studies on the localized biological responses induced by preventive and reparative dental biomaterials.
Using Plant-Based Solutions to Improve Tooth Repair
The NIH funded Laboratory of Applied Dental Biomaterials and Interfaces at UIC College of Dentistry is leading innovations in biomaterials and dental implant research.“When fillings fail, decay forms around it and the seal is lost. Our research is leading to news ways of reinforcing the interface between resin bond and tooth dentin. We're exploring new solutions using natural compounds such as grape seed, to reduce the risk of decay.”
Leme AA, Vidal CM, Hassan LS, Bedran-Russo AK. Potential role of surface wettability on the long-term stability of dentin bonds after surface biomodification. J Biomech. 2015 Jul 16;48(10):2067-71.
Padovano JD, Ravindran S, Snee PT, Ramachandran A, Bedran-Russo AK, George A. DMP1-derived peptides promote remineralization of human dentin. J Dent Res. 2015 Apr;94(4):608-14.
Vidal CM, Leme AA, Aguiar TR, Phansalkar R, Nam JW, Bisson J, McAlpine JB, Chen SN, Pauli GF, Bedran-Russo A. Mimicking the hierarchical functions of dentin collagen cross-links with plant derived phenols and phenolic acids. Langmuir. 2014 Dec 16;30(49):14887-93.
Vidal CM, Aguiar TR, Phansalkar R, McAlpine JB, Napolitano JG, Chen SN, Araújo LS, Pauli GF, Bedran-Russo A. Galloyl moieties enhance the dentin biomodification potential of plant-derived catechins. Acta Biomater. 2014 Jul;10(7):3288-94.
Bedran-Russo AK, Pauli GF, Chen SN, McAlpine J, Castellan CS, Phansalkar RS, Aguiar TR, Vidal CM, Napotilano JG, Nam JW, Leme AA. Dentin biomodification: strategies, renewable resources and clinical applications. Dent Mater. 2014 Jan;30(1):62-76.