James A. Radosevich, PhD

Professor

Research Interests

Dr. Radosevich's laboratory is involved with translational research (bench to bedside and back again) as it relates to various issues of upper aerodigestive tract tumors arising in humans. We use molecular, cellular, immunological, and other methods to explore the biology of these tumors, and to come up with practical, biologically based ways to improve patient treatment.

Publications

Paradise WA, Vesper BJ, Goel A, Waltonen JD, Altman KW, Haines GK, Radosevich JA. 2010. Nitric oxide: perspectives and emerging studies of a well known cytotoxin. Int J Mol Sci.; 11(7):2715-45.

Vesper BJ, Elseth KM, Tarjan G, Haines GK 3rd, Radosevich JA. 2010. Long-term adaptation of breast tumor cell lines to high concentrations of nitric oxide. Tumour Biol.; 31(4):267-75.

Trivedi ER, Vesper BJ, Weitman H, Ehrenberg B, Barrett AG, Radosevich JA, Hoffman BM. 2010. Chiral bis-acetal porphyrazines as near-infrared optical agents for detection and treatment of cancer. Photochem Photobiol.; 86(2):410-7.

Altman KW, Radosevich JA. 2009. Unexpected consequences of proton pump inhibitor use. Otolaryngol Head Neck Surg.; 141(5):564-6.

Vesper, B.J., Jawdi, A., Altman, K.W., Haines III, G.K., Tao, L. and J.A. Radosevich. The Effect of Proton Pump Inhibitors on the Human Microbiota. Current Drug Metabolism 10(1):84-89, 2009.

Altman, M.B., Vesper, B.J., Smith, B.D., Stinauer, M.A., Pelizzari, C.A., Aydogan, B., Reft, C.S., Radosevich, J.A., Chmura, S.J., and J.C. Roeske. Characterization of a Novel Phantom for Three-Dimensional In Vitro Cell Experiments. Physics in Medicine and Biology 54(5):N75-N82, 2009.

Vesper, B.J., Barrentt, A.G.M., Hoffman, B.M., and J.A. Radosevich. Porphyrazine Anti-Tumor Agents, Clinical Chemistry Research. Eds: B.H. Mitchem & C.L. Sharnham., Nova Science Publishers, Hauppauge NY, ISBN: 978-1-60692-517-1, 2009.

Altman, K.W., Paradise, W.A, Vesper, B., and James A. Radosevich. Non-Gastric Proton Pumps As An Adjunctive Mechanism For Acid Secretions. In: Effects, Diagnosis and Management of Exrta-esophageal Reflux: A Multi-disciplinary Approach From World-Renowned Experts In The Field. N. Johnson (Ed). (In Press 2009)

Wilkie, J.R., Roeske, J.C., Tiryaki, H., Smith, B.D, Radosevich, J.A. and B. Aydogan. Feasibility Study for Linac-Based Intensity Modulated Total Marrow Irradiation. Radiation Oncology, Biology & Physics 35(12):5609-18, 2008.

Albrecht, H., Radosevich, J.A., and M. Babich. Fundamentals of antibody-related therapy and diagnostics. Drugs of Today (In Press) 2008.