Research Faculty Member Profile
- Research Assistant Professor
- Research Interests:
- Dr. Chen’s research interests are: angiogenesis and innate immunity including interactions between inflammatory cells, keratinocytes and extra-cellular matrix with fibroblasts in cutaneous and mucosal wound healing.
- Recent Publications:
- Chen L, Marble D, Agha-Majzoub R, Peterson J, Becker RP, Jin TQ, Li JX, Chan LS. 2008. The progression of inflammation parallels the dermal angiogenesis in the keratin-14 IL-4-transgenic model of atopic dermatitis. Microcirculation 15(1):49-64.
- Chen L, Lin SX, Agha-Majzoub R, Overbergh L, Mathieu C, Chan LS. 2006. CCL27 is a critical factor for the development of atopic dermatitis in the keratin-14 interleukin-4 transgenic mouse model. International Immunology 18(8): 1233-1242.
- Chen L, Peterson JD, Zheng WY, Lin SX, Chan LS. 2006. Autoimmunity to type VII collagen in SKH1 mice is independent of regulatory T cells. Clinical Experimental Immunology 145(2): 322-331.
- Chen L, Lin SX, Overbergh L., Mathieu C., and Chan LS. 2005. The disease progression in the keratin 14 IL-4-transgenic mouse model of atopic dermatitis parallels the up-regulation of B cell activation molecules, proliferation and surface and serum IgE. Clinical Experimental Immunology 142(1):21-30.
- Chen L, Martinez O, Overbergh L, Mathieu C, Prabhakar BS, Chan LS. 2004. Early up-regulation of Th2 cytokines and late surge of Th1 cytokines in an atopic dermatitis model. Clinical Experimental Immunology 138(3):375-387.