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| Characterization of proteins involved in Dentin and Bone Mineralization
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Welcome! Our lab at University of Illinois at Chicago , Department of Oral Biology, located on the 4th floor of College of Dentistry. Mineralized
tissues occur widely in nature. In vertebrates bone, teeth and cementum are the principal
mineralized tissues. The shapes of these tissues are defined by their
organic components. In bone, dentin and cementum the organic matrix is comprised principally of collagen fibers and noncollagenous proteins. The fibrous arrays of collagen provide strength, while the rigidity and high compressive strength are derived from the apatite crystals of the mineralized phase, deposited within the collagen fibers. The noncollagenous (NCPs) proteins of bone and dentin, even though present in small quantities
relative to collagen, are of extreme functional importance in the
mineralization process.
Learn more...
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Anne George
Professor
Department of Oral Biology
College of Dentistry
University of Illinois at Chicago
Illinois
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