Seunghyuk Chung, PhD

Assistant Professor

chungsh@uic.edu

Education & Career

  • University of Calgary, Canada, PhD (Neuroscience), 2008
  • University of California, Davis, Postdoctoral Fellow, 2009-2013 

Teaching

  • DBCS 311-313 Histology & Lab
  • HSTL 506 Periodontal Structures and Function

Clinical and Research Interests

  • The role of p38 MAP kinase and chromatin remodeling factor Brg1 in nerve myelination and odontoblast differentiation
  • Regenerative and pharmacological approaches to find a relevant cure for cerebral palsy and multiple sclerosis using mouse models of periventricular leukomalacia and experimental autoimmune encephalomyelitis
  • Cerebellar compartmentation and development

Publications

Chung SH, Guo F, Jiang P, Pleasure E, Deng W (2013) Olig2/Plp progenitor cells give rise to Bergmann glia in the cerebellum. Cell Death and Disease 4,e546

Jiang P, Chen C, Wang R, Chechneva O, Liu Y, Chung SH, Daugherty D, Han D, Rao M, Pleasure D, Zhang Q, Deng W (2013) Human astroglial transplants generated from embryonic stem cell derived Olig2+ progenitors are highly protective against ischemic brain injury and improve functional outcome. Nature Communications 4:2196

Chung SH, Calafiore M, Plane JM, Pleasure, DE, Deng W (2011) Apoptosis inducing factor deficiency causes reduced Mitofusion1 expression and patterned Purkinje cell degeneration. Neurobiology of Disease 41:445-457

Chung SH, Marzban H, Aldinger K, Millen K, Schuurmans C, Hawkes R (2011) Zac1 plays a key role in the development of specific neuronal subsets in the mouse cerebellum. Neural Development 6:25

Chung SH, Kim CT, Jeong YG, Lee NS (2010) Tbr2-immunopositive unipolar brush cells are associated with ectopic zebrin II-immunoreactive Purkinje cell clusters in the cerebellum of scrambler mice. Anatomy and Cell Biology 43:72-77

Armstrong CL, Chung SH, Armstrong JN, Hochgeschwender U, Jeong YG, Hawkes R (2009) A novel somatostatin-immunoreactive mossy fiber pathway associated with HSP25-immunoreactive purkinje cell stripes in the mouse cerebellum. Journal of Comparative Neurology 517:524-38

Chung SH, Sillitoe RV, Croci L, Badaloni A, Consalez G, Hawkes R (2009) Purkinje cell phenotype restricts the distribution of unipolar brush cells. Neuroscience 164:1496-1508

Chung SH, Marzban H, Watanabe M, Hawkes R (2009) Phospholipase C¿4 expression reveals a novel subset of unipolar brush cells in the adult mouse cerebellum. Cerebellum 3:267-276

Chung SH, Marzban H, Hawkes R (2009) Compartmentation of the cerebellar nuclei of the mouse. Neuroscience 161:123-138

Sillitoe RV, Chung SH, Fritschy JM, Hoy M, Hawkes R (2008) Golgi cell dendrites are restricted by Purkinje cell stripe boundaries in the adult mouse cerebellar cortex. Journal of Neuroscience 28:2820-2826

Chung SH, Kim CT, Hawkes R (2008) Compartmentation of GABA B receptor2 expression in the mouse cerebellar cortex. Cerebellum 27:1-9

Chung SH, Marzban H, Croci L, Consalez GG, Hawkes R (2008) Purkinje cell subtype specification in the cerebellar cortex: Ebf2 acts to repress the zebrin II-positive Purkinje cell phenotype. Neuroscience 153:721-732