Hervé Y. Sroussi, DMD, PhD

Associate Professor
Chief of Oral Medicine Research

sroussih@uic.edu
UICollaboratory Profile

Research Interests

Dr. Sroussi's research interests include the oxidative regulation of inflammation and wound healing. Specifically, Dr Sroussi studies the regulation of leukocyte migration and activation by S100 proteins. Dr. Sroussi's other research interests include auto-immune and infectious diseases of the mouth; oral cancer and early detection of cancerous and pre-cancerous lesions and oral manifestations of HIV.

Publications

Sroussi HY, Burke-Miller J, French AL, Adeyemi OM, Weber KM, Lu Y, Cohen M. Association among Vitamin D, Oral Candidiasis, and Calprotectinemia in HIV. J Dent Res. 2012 Jul;91(7):666-70. Epub 2012 Apr 25.

Williams RL, Sroussi HY, Abercrombie JJ, Leung K, Marucha PT. Synthetic decapeptide reduces bacterial load and accelerates healing in the wounds of restraint-stressed mice. Brain Behav Immun. 2012 May;26(4):588-96. Epub 2012 Feb 6.

Sroussi HY, Lu Y, Villines D, Sun Y. The down regulation of neutrophil oxidative metabolism by S100A8 and S100A9: implication of the protease-activated receptor-2. Mol Immunol. 2012 Feb;50(1-2):42-8. Epub 2011 Dec 26.

Williams RL, Sroussi HY, Leung K, Marucha PT. Antimicrobial decapeptide KSL-W enhances neutrophil chemotaxis and function. Peptides. 2012 Jan;33(1):1-8. Epub 2011 Dec 16.

Kolokythas A, Schwartz JL, Pytynia KB, Panda S, Yao M, Homann B, Sroussi HY, Epstein JB, Gordon SC, Adami GR. Analysis of RNA from brush cytology detects changes in B2M, CYP1B1 and KRT17 levels with OSCC in tobacco users. Oral Oncol. 2011 Jun;47(6):532-6. Epub 2011 May 5.

Tugizov SM, Webster-Cyriaque JY, Syrianen S, Chattopadyay A, Sroussi H, Zhang L, Kaushal A. Mechanisms of viral infections associated with HIV: workshop 2B. Adv Dent Res. 2011 Apr;23(1):130-6.

Schwartz R, Lu Y, Villines D, Sroussi HY. Effect of human immunodeficiency virus infection on S100A8/A9 inhibition of peripheral neutrophils oxidative metabolism. Biomed Pharmacother. 2010 Oct;64(8):572-5. Epub 2010 May 8.

Sroussi HY, Lu Y, Zhang QL, Villines D, Marucha PT. S100A8 and S100A9 inhibit neutrophil oxidative metabolism in-vitro: involvement of adenosine metabolites. Free Radic Res. 2010 Apr;44(4):389-96.

Sroussi HY, Williams RL, Zhang QL, Villines D, Marucha PT. Ala42S100A8 ameliorates psychological-stress impaired cutaneous wound healing. Brain Behav Immun. 2009 Aug;23(6):755-9. Epub 2009 Mar 29.

Epstein JB, Sciubba J, Silverman S Jr, Sroussi HY. 2007. Utility of toluidine blue in oral premalignant lesions and squamous cell carcinoma: continuing research and implications for clinical practice. Head Neck 29(10):948-58.

Research Areas