The Center for Molecular Biology of Oral Diseases was founded in 1980 as a multidisciplinary unit devoted to understanding basic pathobiological mechanisms relevant to oral diseases. Although this remains an overall theme of ongoing research in the Center, current faculty interests are becoming increasingly focused in the area of cancer biology with an emphasis on oral cancer. This change of focus reflects the Center’s commitment to a new interdisciplinary thematic program in oral/ head and neck cancer as part of the UIC Cancer Center. This program involves other Departments in the College of Dentistry as well as other Colleges in the university.
The goals of the program are to make use of the basic research findings in cancer biology to develop new treatments for head and neck cancer patients, and to develop new molecular diagnostic tools to better assess clinical outcomes in patients at risk for oral cancer. The ongoing studies of the program include ways to prevent, detect, diagnose, predict, and treat oral cancer. Center faculty perform basic and translational research in these areas utilizing state-of-the-art genomic and proteomic approaches and are engaged in teaching undergraduate, graduate, and postgraduate students both in the laboratory and in the classroom.
Faculty are currently funded by the National Institutes of Health, the American Institute for Cancer Research, the Susan G. Komen Breast Cancer Foundation and the Illinois Department of Public Health. Linking advances in our understanding of cancer biology with improved methods of early detection, diagnosis, and prognosis of oral cancers is the key mission of the oral cancer program.
The Oral Cancer Journal Club meets in the third Tuesday of every month from 12-1 pm. For more information please contact Dr. David Crowe (312.996.9488).
Graduate training availible through the PhD in Oral Sciences.
University of Illinois at Chicago Cancer Center
National Institutes of Health
The National Cancer Institute
US National Library of Medicine
The Oral Cancer Foundation