Tissue engineering is a process by which new tissues are generated to replace, repair, or aid existing tissues. Usually, tissue engineering is based upon biomimetic or bioinspired strategies; i.e. the tissue engineer utilizes principles found in nature to generate novel tissues. Today, tissue engineering reaches beyond merely copying or mimicking natural processes. One aspect of tissue engineering has increasingly become a synthetic science in which concepts found in biological organisms are utilized to fabricate novel, biocompatible materials, often based on nanotechnology. A second trend in tissue engineering has developed in which the bioinductive properties of molecules are exploited to induce the regeneration of lost or deficient tissues. Classic concepts of tissue engineering are founded on the "Tissue Engineering Triad" consisting of cells (usually stem cells or inducible pluripotent cells), signaling systems, and matrices (scaffolds). These concepts are based on the paradigm that in order to replace or repair a normal tissue environment, all three components of natural tissues have to be rebuilt: cells, molecules, and the extracellular matrix environment, in which cells and molecules occur. Dr. Luan's research is part of the Brodie Laboratory for Craniofacial Genetics.
Please explore this review of the research performed in Dr. Luan's lab.
Dr. Xianghong Luan
Department of Oral Biology (MC 690)
801 South Paulina Street
Chicago, Illinois 60612