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A MULTIDISCIPLINARY RESEARCH ENVIRONMENT |
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Our laboratory features a broad spectrum of research areas and technologies. Areas of research range from stem cell biology and tissue engineering to the developmental and evolutionary biology of odontogenic tissues. One area of expertise includes the use of classic and modern structural analysis techniques such as paraffin histology, ultrathin ground sections, scanning and transmission electron microscopy, immunohisto- and cytochemistry, and atomic force microscopy. A second area of research in our lab focuses on proteins, using recombinant technology and structural biology approaches such as 3D NMR to decipher the structure of proteins in their biological environments. The molecular biology team in our lab uses promoter studies, in situ and real-time RT-PCR to study gene expression. For gene function studies, we use transgenic and knockout mouse models in tandem with knockdown and overexpression cell culture approaches. Most recently, we are employing microarray-based technologies to study global changes in gene expression. Finally, we are also equipped for tissue regeneration and tooth movement studies in rats and mice. Based on the broad range of technologies used and questions asked, the Brodie Laboratory is an ideal training environment for graduate students and junior scientists. |
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RESEARCH AND TRAINING |
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The Brodie lab is supported by grants from the National Institute of Dental and Craniofacial Research. |
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Cameron G. Walker, UIC’s first D.D.S./Ph.D. student, after defending his Ph.D. thesis on “Tissue Remodeling and Factors Governing Tooth Movement”. |
Visit to the Field Museum as part of the 2009 Summer Research Program for Students and Science Educators as facilitated by the National Institutes of Health ARRA Administrative Supplements (l. to r. Caryn Reizl Ayarzagoitia, Lena deBaz, and Kes Schroer). |
